AutismKB 2.0

Annotation Details for PIP4K2B


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:PIP4K2B ( PI5P4KB,PIP5K2B,PIP5KIIB,PIP5KIIbeta )
Gene Full Name: phosphatidylinositol-5-phosphate 4-kinase, type II, beta
Band: 17q12
Quick LinksEntrez ID:8396; OMIM: 603261; Uniprot ID:PI42B_HUMAN; ENSEMBL ID: ENSG00000141720; HGNC ID: 8998
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005654IDA-nucleoplasm-
GO:0005654TAS-nucleoplasm-
GO:0005776IMP-autophagosome25578879
GO:0005789IEA-endoplasmic reticulum membrane-
GO:0005829TAS-cytosol-
GO:0005886IEA-plasma membrane-
GO ID Evidence Qualifier GO_term References
GO:0005057TAS-signal transducer activity, downstream of receptor9038203
GO:0005515IPI-protein binding25416956
GO:0005524IEA-ATP binding-
GO:0016308IDA-1-phosphatidylinositol-4-phosphate 5-kinase activity9038203
GO:0016309EXP-1-phosphatidylinositol-5-phosphate 4-kinase activity23758345
GO:0016309TAS-1-phosphatidylinositol-5-phosphate 4-kinase activity-
GO:0042803IDA-protein homodimerization activity9753329
GO:0052811TAS-1-phosphatidylinositol-3-phosphate 4-kinase activity-
GO ID Evidence Qualifier GO_term References
GO:0006644TAS-phospholipid metabolic process-
GO:0006661TAS-phosphatidylinositol biosynthetic process-
GO:0007166TAS-cell surface receptor signaling pathway9038203
GO:0010506IMP-regulation of autophagy25578879
GO:0014066TAS-regulation of phosphatidylinositol 3-kinase signaling-
GO:0046854IEA-phosphatidylinositol phosphorylation-
GO:2000786IMP-positive regulation of autophagosome assembly25578879
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
PIP4K2BTNFRSF1A1129869038203 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
PIP4K2BTNFRSF1A1139859038203 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
PIP4K2BPIP4K2B1139859753329 Co-crystal Structure
No data
No data
AlzGene, PDGene and SZGene Top
No data
No data
Gene Symbol Poly Names Gene overview in SZGene
PIP4K2Brs115327, rs12453325, rs2075061, rs228232, rs228295, rs228307, rs2338115, rs3744070 Gene overview in SZGene
Animal Model Top
  • MGI ID: MGI:1934234
  • Data Attributes: MGI curated and HomoloGene calculated
No data