AutismKB 2.0

Annotation Details for PLA2G6


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Basic Information Top
Gene Symbol:PLA2G6 ( CaI-PLA2,GVI,INAD1,IPLA2-VIA,NBIA2A,NBIA2B,PARK14,PLA2,PNPLA9,iPLA2 )
Gene Full Name: phospholipase A2, group VI (cytosolic, calcium-independent)
Band: 22q13.1
Quick LinksEntrez ID:8398; OMIM: 603604; Uniprot ID:PA2G6_HUMAN; ENSEMBL ID: ENSG00000184381; HGNC ID: 9039
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005615IDA-extracellular space18714013
GO:0005739IEA-mitochondrion-
GO:0005815IDA-microtubule organizing center-
GO:0005829IDA-cytosol-
GO:0005829TAS-cytosol-
GO:0016020IEA-membrane-
GO ID Evidence Qualifier GO_term References
GO:0004623TAS-phospholipase A2 activity-
GO:0005516IEA-calmodulin binding-
GO:0016787TAS-hydrolase activity-
GO:0019901IEA-protein kinase binding-
GO:0043008IEA-ATP-dependent protein binding-
GO:0047499IEA-calcium-independent phospholipase A2 activity-
GO ID Evidence Qualifier GO_term References
GO:0001934IEA-positive regulation of protein phosphorylation-
GO:0006935IEA-chemotaxis-
GO:0007204IEA-positive regulation of cytosolic calcium ion concentration-
GO:0007613IEA-memory-
GO:0014832IEA-urinary bladder smooth muscle contraction-
GO:0016042IEA-lipid catabolic process-
GO:0019731IDA-antibacterial humoral response18714013
GO:0032049IMP-cardiolipin biosynthetic process19164547
GO:0034976IEA-response to endoplasmic reticulum stress-
GO:0035774IEA-positive regulation of insulin secretion involved in cellular response to glucose stimulus-
GO:0036151TAS-phosphatidylcholine acyl-chain remodeling-
GO:0036152TAS-phosphatidylethanolamine acyl-chain remodeling-
GO:0038096TAS-Fc-gamma receptor signaling pathway involved in phagocytosis-
GO:0045921IEA-positive regulation of exocytosis-
GO:0051967IEA-negative regulation of synaptic transmission, glutamatergic-
GO:0060135IEA-maternal process involved in female pregnancy-
GO:0090037IEA-positive regulation of protein kinase C signaling-
GO:0090200IEA-positive regulation of release of cytochrome c from mitochondria-
GO:0090238IEA-positive regulation of arachidonic acid secretion-
GO:0097755IEA-positive regulation of blood vessel diameter-
GO:1901339IEA-regulation of store-operated calcium channel activity-
GO:2000304IEA-positive regulation of ceramide biosynthetic process-
Protein-Protein Interaction Top
AlzGene, PDGene and SZGene Top
No data
No data
Gene Symbol Poly Names Gene overview in SZGene
PLA2G6rs2235346, rs2272831, rs2284060, rs4375 Gene overview in SZGene
Animal Model Top
  • MGI ID: MGI:1859152
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-040426-2079'