AutismKB 2.0

Annotation Details for PLA2G10


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Basic Information Top
Gene Symbol:PLA2G10 ( GXPLA2,GXSPLA2,MGC119918,MGC119919,MGC133367,SPLA2 )
Gene Full Name: phospholipase A2, group X
Band: 16p13.12
Quick LinksEntrez ID:8399; OMIM: 603603; Uniprot ID:PA2GX_HUMAN; ENSEMBL ID: ENSG00000069764; HGNC ID: 9029
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005576TAS-extracellular region-
GO:0005615IDA-extracellular space21805676
GO ID Evidence Qualifier GO_term References
GO:0004620ISS-phospholipase activity20844270
GO:0004623TAS-phospholipase A2 activity-
GO:0005509IEA-calcium ion binding-
GO ID Evidence Qualifier GO_term References
GO:0006654TAS-phosphatidic acid biosynthetic process-
GO:0007411IDA-axon guidance15927955
GO:0010744IC-positive regulation of macrophage derived foam cell differentiation18511424
GO:0010884IMP-positive regulation of lipid storage18511424
GO:0016042IEA-lipid catabolic process-
GO:0019369NAS-arachidonic acid metabolic process18511424
GO:0032270IMP-positive regulation of cellular protein metabolic process18511424
GO:0032308IMP-positive regulation of prostaglandin secretion18511424
GO:0036148TAS-phosphatidylglycerol acyl-chain remodeling-
GO:0036149TAS-phosphatidylinositol acyl-chain remodeling-
GO:0036150TAS-phosphatidylserine acyl-chain remodeling-
GO:0036151TAS-phosphatidylcholine acyl-chain remodeling-
GO:0036152TAS-phosphatidylethanolamine acyl-chain remodeling-
GO:0042632ISS-cholesterol homeostasis20844270
GO:0043030IMP-regulation of macrophage activation18511424
GO:0043433IDA-negative regulation of sequence-specific DNA binding transcription factor activity20844270
GO:0050482IEA-arachidonic acid secretion-
GO:0051977IDA-lysophospholipid transport15927955
GO:0090238ISS-positive regulation of arachidonic acid secretion20844270
GO:0090370ISS-negative regulation of cholesterol efflux20844270
Protein-Protein Interaction Top
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1347522
  • Data Attributes: MGI curated and HomoloGene calculated
No data