AutismKB 2.0

Annotation Details for CASP7


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Basic Information Top
Gene Symbol:CASP7 ( CMH-1,ICE-LAP3,MCH3 )
Gene Full Name: caspase 7, apoptosis-related cysteine peptidase
Band: 10q25.3
Quick LinksEntrez ID:840; OMIM: 601761; Uniprot ID:CASP7_HUMAN; ENSEMBL ID: ENSG00000165806; HGNC ID: 1508
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634IDA-nucleus17167422
GO:0005654TAS-nucleoplasm-
GO:0005737TAS-cytoplasm8576161
GO:0005829IDA-cytosol17167422
GO:0005829TAS-cytosol-
GO ID Evidence Qualifier GO_term References
GO:0004197TAS-cysteine-type endopeptidase activity-
GO:0005515IPI-protein binding11084335
GO:0008233IDA-peptidase activity19740745
GO:0008234TAS-cysteine-type peptidase activity8567622
GO:0097200IBA-cysteine-type endopeptidase activity involved in execution phase of apoptosis-
GO:0097200IMP-cysteine-type endopeptidase activity involved in execution phase of apoptosis22253444
GO ID Evidence Qualifier GO_term References
GO:0006508IDA-proteolysis12888622
GO:0006915TAS-apoptotic process8567622
GO:0008635TAS-activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c-
GO:0072734IMP-cellular response to staurosporine22253444
GO:0097194IBA-execution phase of apoptosis-
GO:0097194TAS-execution phase of apoptosis-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
CASP7BIRC21068269384571 Reconstituted Complex
CASP7BIRC21072909384571 Reconstituted Complex
CASP7BIRC31068279384571 Reconstituted Complex
CASP7BIRC31072909384571 Reconstituted Complex
CASP7XIAP1068289230442 9384571 11257232 11359776 Reconstituted Complex
CASP7XIAP1072909230442 9384571 11257232 11359776 Reconstituted Complex
CASP7BIRC51068299850056 11170436 Biochemical Activity; Reconstituted Complex
CASP7BIRC51072909850056 11170436 Biochemical Activity; Reconstituted Complex
CASP7CASP210728511399776 Biochemical Activity
CASP7CASP210729011399776 Biochemical Activity
CASP8CASP71072918962078 11832478 Biochemical Activity
CASP8CASP71072908962078 11832478 Biochemical Activity
CASP10CASP71072938962078 Biochemical Activity
CASP10CASP71072908962078 Biochemical Activity
BIRC7CASP712267011024045 Reconstituted Complex
BIRC7CASP710729011024045 Reconstituted Complex
TNFRSF1ACASP711298611755217 Biochemical Activity
TNFRSF1ACASP710729011755217 Biochemical Activity
HSPA5CASP710954111943137 Affinity Capture-Western
HSPA5CASP710729011943137 Affinity Capture-Western
Gene Symbol Interactant Interaction ID References Description
BIRC6CASP718058015200957 BRUCE interacts with Casp-7. This interaction was modeled on a demonstrated interaction between mouse BRUCE and human Casp-7.
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:109383
  • Data Attributes: MGI curated and HomoloGene calculated
No data