AutismKB 2.0

Annotation Details for ULK1


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Basic Information Top
Gene Symbol:ULK1 ( ATG1,ATG1A,FLJ38455,FLJ46475,UNC51,Unc51.1 )
Gene Full Name: unc-51-like kinase 1 (C. elegans)
Band: 12q24.33
Quick LinksEntrez ID:8408; OMIM: 603168; Uniprot ID:ULK1_HUMAN; ENSEMBL ID: ENSG00000177169; HGNC ID: 12558
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005737NAS-cytoplasm9693035
GO:0005741TAS-mitochondrial outer membrane-
GO:0005776IDA-autophagosome17595159
GO:0005789TAS-endoplasmic reticulum membrane-
GO:0005829IDA-cytosol11146101
GO:0005829TAS-cytosol-
GO:0032045IDAcolocalizes_withguanyl-nucleotide exchange factor complex27103069
GO:0034045IDA-pre-autophagosomal structure membrane18936157
GO:0055037TAS-recycling endosome-
GO:0097629IDA-extrinsic component of omegasome membrane22885598
GO:0097632IDA-extrinsic component of pre-autophagosomal structure membrane22885598
GO:0097635IDA-extrinsic component of autophagosome membrane22885598
GO:1990316IPI-ATG1/ULK1 kinase complex19211835
GO ID Evidence Qualifier GO_term References
GO:0004674IDA-protein serine/threonine kinase activity18936157
GO:0004674NAS-protein serine/threonine kinase activity9693035
GO:0004674TAS-protein serine/threonine kinase activity-
GO:0005515IPI-protein binding11146101
GO:0005524IEA-ATP binding-
GO:0016301TAS-kinase activity-
GO:0017137IPI-Rab GTPase binding22613832
GO:0032403IPI-protein complex binding19211835
GO:0051020IPI-GTPase binding25891078
GO ID Evidence Qualifier GO_term References
GO:0006468NAS-protein phosphorylation9693035
GO:0006914IDA-autophagy18936157
GO:0006914IMP-autophagy17595159
GO:0006914ISS-autophagy-
GO:0007165IEA-signal transduction-
GO:0008104IMP-protein localization16940348
GO:0016236IMP-macroautophagy22354037
GO:0016236TAS-macroautophagy-
GO:0016241TAS-regulation of macroautophagy-
GO:0018105IDA-peptidyl-serine phosphorylation25126726
GO:0018107IDA-peptidyl-threonine phosphorylation27103069
GO:0031102IEA-neuron projection regeneration-
GO:0031175IMP-neuron projection development18007665
GO:0031333IDA-negative regulation of protein complex assembly25126726
GO:0031669ISS-cellular response to nutrient levels-
GO:0042594ISS-response to starvation-
GO:0046777IDA-protein autophosphorylation18936157
GO:0048675IBA-axon extension-
GO:0061024TAS-membrane organization-
GO:0075044IGI-autophagy of host cells involved in interaction with symbiont28389568
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
ULK1PRKAA111154920562859 Affinity Capture-MS
ULK1PRKAA111399620562859 Affinity Capture-MS
ULK1PRKAA211399620562859 Affinity Capture-MS
ULK1PRKAA211155020562859 Affinity Capture-MS
ULK1PRKAB211155220562859 Affinity Capture-MS
ULK1PRKAB211399620562859 Affinity Capture-MS
ULK1PRKAG111399620562859 Affinity Capture-MS
ULK1PRKAG111155820562859 Affinity Capture-MS
ULK1SDCBP11228715014045 Affinity Capture-Western; Two-hybrid
ULK1SDCBP11399615014045 Affinity Capture-Western; Two-hybrid
GABARAPULK111646511146101 17353931 Affinity Capture-MS; Reconstituted Complex; Two-hybrid
GABARAPULK111399611146101 17353931 Affinity Capture-MS; Reconstituted Complex; Two-hybrid
GABARAPL2ULK111647311146101 20562859 Affinity Capture-MS; Reconstituted Complex; Two-hybrid
GABARAPL2ULK111399611146101 20562859 Affinity Capture-MS; Reconstituted Complex; Two-hybrid
SYNGAP1ULK111435815014045 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
SYNGAP1ULK111399615014045 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
G3BP1ULK111399620562859 Affinity Capture-MS
G3BP1ULK111544820562859 Affinity Capture-MS
CDC37ULK111399620562859 Affinity Capture-MS
CDC37ULK111631220562859 Affinity Capture-MS
ATG4BULK111680120562859 Affinity Capture-MS
ATG4BULK111399620562859 Affinity Capture-MS
USP10ULK111399620562859 Affinity Capture-MS
USP10ULK111455420562859 Affinity Capture-MS
RB1CC1ULK111399620562859 Affinity Capture-MS
RB1CC1ULK111516020562859 Affinity Capture-MS
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1270126
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-071203-2'