AutismKB 2.0

Annotation Details for ANTXR1


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Basic Information Top
Gene Symbol:ANTXR1 ( ATR,FLJ10601,FLJ11298,FLJ21776,TEM8 )
Gene Full Name: anthrax toxin receptor 1
Band: 2p13.3
Quick LinksEntrez ID:84168; OMIM: 606410; Uniprot ID:ANTR1_HUMAN; ENSEMBL ID: ENSG00000169604; HGNC ID: 21014
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005886TAS-plasma membrane-
GO:0009897IDA-external side of plasma membrane21129411
GO:0009986IDA-cell surface19581412
GO:0010008TAS-endosome membrane-
GO:0016021IEA-integral component of membrane-
GO:0031258IDA-lamellipodium membrane16762926
GO:0031527IDA-filopodium membrane16762926
GO:0070062IDA-extracellular exosome23376485
GO ID Evidence Qualifier GO_term References
GO:0004888IDA-transmembrane signaling receptor activity16762926
GO:0005515IPI-protein binding14507921
GO:0005518IDA-collagen binding16762926
GO:0046872IEA-metal ion binding-
GO:0051015IDA-actin filament binding16762926
GO ID Evidence Qualifier GO_term References
GO:0001568IEA-blood vessel development-
GO:0007165IEA-signal transduction-
GO:0022414IEA-reproductive process-
GO:0031532IDA-actin cytoskeleton reorganization16762926
GO:0034446IDA-substrate adhesion-dependent cell spreading16762926
GO:1901202IEA-negative regulation of extracellular matrix assembly-
GO:1905050IEA-positive regulation of metallopeptidase activity-
Protein-Protein Interaction Top
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1916788
  • Data Attributes: MGI curated and HomoloGene calculated
No data
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  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018