AutismKB 2.0

Annotation Details for STX7


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:STX7 ( - )
Gene Full Name: syntaxin 7
Band: 6q23.2
Quick LinksEntrez ID:8417; OMIM: 603217; Uniprot ID:STX7_HUMAN; ENSEMBL ID: ENSG00000079950; HGNC ID: 11442
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0001772IDA-immunological synapse21438968
GO:0005764IDA-lysosome18980942
GO:0005765IDA-lysosomal membrane17897319
GO:0005768IDA-endosome10564279
GO:0005769IDA-early endosome10564279
GO:0005770IDA-late endosome18980942
GO:0005886IDA-plasma membrane18980942
GO:0016021IBA-integral component of membrane-
GO:0030139IDA-endocytic vesicle10564279
GO:0031201IBA-SNARE complex-
GO:0031901IEA-early endosome membrane-
GO:0031982IDA-vesicle18570918
GO:0042582IDA-azurophil granule20170677
GO:0048471IDA-perinuclear region of cytoplasm18570918
GO:0055037IDA-recycling endosome18570918
GO:0070062IDA-extracellular exosome20458337
GO:0070820IDA-tertiary granule20170677
GO ID Evidence Qualifier GO_term References
GO:0000149IDA-SNARE binding24550300
GO:0005484IBA-SNAP receptor activity-
GO:0005515IPI-protein binding11382755
GO:0019869IDA-chloride channel inhibitor activity18570918
GO:0019905IPI-syntaxin binding10564279
GO ID Evidence Qualifier GO_term References
GO:0001916IMP-positive regulation of T cell mediated cytotoxicity21438968
GO:0006886IBA-intracellular protein transport-
GO:0006906IBA-vesicle fusion-
GO:0048278IBA-vesicle docking-
GO:0051640IDA-organelle localization21438968
GO:0065009IEA-regulation of molecular function-
GO:0070925IDA-organelle assembly21438968
GO:1902685IMP-positive regulation of receptor localization to synapse21438968
GO:1903076IDA-regulation of protein localization to plasma membrane18570918
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
STX7GTF2I11400311278762 Affinity Capture-MS
STX7GTF2I10922411278762 Affinity Capture-MS
STX7NSF11096020562859 Affinity Capture-MS
STX7NSF11400320562859 Affinity Capture-MS
NAPASTX71143059417091 Reconstituted Complex
NAPASTX71140039417091 Reconstituted Complex
SNAP29STX71147489852078 Reconstituted Complex
SNAP29STX71140039852078 Reconstituted Complex
VAMP8STX711422111101518 11278762 Affinity Capture-MS; Affinity Capture-Western; Co-purification
VAMP8STX711400311101518 11278762 Affinity Capture-MS; Affinity Capture-Western; Co-purification
VTI1ASTX712678911101518 Affinity Capture-Western
VTI1ASTX711400311101518 Affinity Capture-Western
STX8STX711486711101518 Affinity Capture-Western
STX8STX711400311101518 Affinity Capture-Western
STX6STX711552211278762 Affinity Capture-MS
STX6STX711400311278762 Affinity Capture-MS
VPS11STX711400311382755 Affinity Capture-Western
VPS11STX712093011382755 Affinity Capture-Western
VPS18STX712166411382755 Affinity Capture-Western
VPS18STX711400311382755 Affinity Capture-Western
VTI1BSTX711575312114520 Reconstituted Complex
VTI1BSTX711400312114520 Reconstituted Complex
No data
No data
AlzGene, PDGene and SZGene Top
No data
No data
Gene Symbol Poly Names Gene overview in SZGene
STX7rs1044083, rs11757447, rs12207033, rs1591811, rs17191957, rs1856352, rs2153177, rs2788942, rs2842884, rs2842885, rs3183732, rs3757298, rs3757299, rs3765577, rs3800204, rs3813356, rs3813357, rs4470875, rs6939077, rs7758872, rs9321344, rs9321345, rs9321346, rs9483455, rs9483457, rs9483458, rs9493355 Gene overview in SZGene
Animal Model Top
  • MGI ID: MGI:1858210
  • Data Attributes: MGI curated and HomoloGene calculated
No data
No data

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018