AutismKB 2.0

Annotation Details for TRAF7


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Basic Information Top
Gene Symbol:TRAF7 ( DKFZp586I021,MGC7807,RFWD1,RNF119 )
Gene Full Name: TNF receptor-associated factor 7
Band: 16p13.3
Quick LinksEntrez ID:84231; OMIM: 606692; Uniprot ID:TRAF7_HUMAN; ENSEMBL ID: ENSG00000131653; HGNC ID: 20456
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0000151IDA-ubiquitin ligase complex14743216
GO:0005886IDA-plasma membrane-
GO:0031410IEA-cytoplasmic vesicle-
GO:0043231IDA-intracellular membrane-bounded organelle-
GO ID Evidence Qualifier GO_term References
GO:0004842IDA-ubiquitin-protein transferase activity14743216
GO:0005515IPI-protein binding14743216
GO:0008270NAS-zinc ion binding14743216
GO ID Evidence Qualifier GO_term References
GO:0000185IDA-activation of MAPKKK activity14743216
GO:0006351IEA-transcription, DNA-templated-
GO:0006355IEA-regulation of transcription, DNA-templated-
GO:0006915IDA-apoptotic process15001576
GO:0016567IDA-protein ubiquitination14743216
GO:0016567IEA-protein ubiquitination-
GO:0043410IDA-positive regulation of MAPK cascade15001576
GO:2001235IMP-positive regulation of apoptotic signaling pathway15001576
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
TRAF7UBE2K10934019549727 Two-hybrid
TRAF7UBE2K12396419549727 Two-hybrid
TRAF7MAP3K311037914743216 Affinity Capture-MS
TRAF7MAP3K312396414743216 Affinity Capture-MS
TRAF7UBE2D112396419549727 Two-hybrid
TRAF7UBE2D111316919549727 Two-hybrid
TRAF7UBE2D211317019549727 Two-hybrid
TRAF7UBE2D212396419549727 Two-hybrid
TRAF7UBE2L311318019549727 Two-hybrid
TRAF7UBE2L312396419549727 Two-hybrid
TRAF7UBE2L611467219549727 Two-hybrid
TRAF7UBE2L612396419549727 Two-hybrid
TRAF7UBE2D411964119549727 Two-hybrid
TRAF7UBE2D412396419549727 Two-hybrid
Gene Symbol Interactant Interaction ID References Description
TRAF7MAP3K320998614743216 TRAF7 interacts with an unspecified isoform of MAP3K3 (MEKK3).
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:3042141
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-070112-2212'