AutismKB 2.0

Annotation Details for VPS25


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Basic Information Top
Gene Symbol:VPS25 ( DERP9,EAP20,FAP20,MGC10540 )
Gene Full Name: vacuolar protein sorting 25 homolog (S. cerevisiae)
Band: 17q21.31
Quick LinksEntrez ID:84313; OMIM: 610907; Uniprot ID:VPS25_HUMAN; ENSEMBL ID: ENSG00000131475; HGNC ID: 28122
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0000814TAS-ESCRT II complex20588296
GO:0005634IDA-nucleus16371348
GO:0005654IEA-nucleoplasm-
GO:0005737IDA-cytoplasm16973552
GO:0005829IDA-cytosol17010938
GO:0005829TAS-cytosol-
GO:0010008IDA-endosome membrane16371348
GO:0070062IDA-extracellular exosome19056867
GO ID Evidence Qualifier GO_term References
GO:0005198IBA-structural molecule activity-
GO:0005515IPI-protein binding14505570
GO:0042803IPI-protein homodimerization activity14519844
GO:0047485IPI-protein N-terminus binding16973552
GO ID Evidence Qualifier GO_term References
GO:0006351IEA-transcription, DNA-templated-
GO:0006355IEA-regulation of transcription, DNA-templated-
GO:0016197TAS-endosomal transport-
GO:0016236TAS-macroautophagy20588296
GO:0036258TAS-multivesicular body assembly20588296
GO:0043328IBA-protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway-
GO:1903900IDANOTregulation of viral life cycle16973552
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
VPS25SNF812403916189514 16371348 Reconstituted Complex; Two-hybrid
VPS25SNF811642516189514 16371348 Reconstituted Complex; Two-hybrid
VPS25VPS3612403916371348 Reconstituted Complex; Two-hybrid
VPS25VPS3611923416371348 Reconstituted Complex; Two-hybrid
VPS25APIP11926516189514 Two-hybrid
VPS25APIP12403916189514 Two-hybrid
VPS25CHMP612277116371348 Two-hybrid
VPS25CHMP612403916371348 Two-hybrid
RHOXF2VPS2512411916189514 Two-hybrid
RHOXF2VPS2512403916189514 Two-hybrid
VPS25VPS2512403916371348 Reconstituted Complex; Two-hybrid
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:106354
  • Data Attributes: MGI curated and HomoloGene calculated
No data