AutismKB 2.0

Annotation Details for CARD11


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Basic Information Top
Gene Symbol:CARD11 ( BIMP3,CARMA1,MGC133069 )
Gene Full Name: caspase recruitment domain family, member 11
Band: 7p22.2
Quick LinksEntrez ID:84433; OMIM: 607210; Uniprot ID:CAR11_HUMAN; ENSEMBL ID: ENSG00000198286; HGNC ID: 16393
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0001772IEA-immunological synapse-
GO:0005737IDA-cytoplasm12154360
GO:0005829TAS-cytosol-
GO:0005886IDA-plasma membrane12154360
GO:0005886TAS-plasma membrane-
GO:0042101IDAcolocalizes_withT cell receptor complex12154360
GO:0045121IDA-membrane raft12154360
GO:0070062IDA-extracellular exosome18570454
GO ID Evidence Qualifier GO_term References
GO:0004385NAS-guanylate kinase activity11278692
GO:0005515IPI-protein binding16809782
GO:0050700IPI-CARD domain binding11278692
GO ID Evidence Qualifier GO_term References
GO:0001819IMP-positive regulation of cytokine production12154360
GO:0002223TAS-stimulatory C-type lectin receptor signaling pathway-
GO:0002377IEA-immunoglobulin production-
GO:0030183IEA-B cell differentiation-
GO:0030890IEA-positive regulation of B cell proliferation-
GO:0031295IDA-T cell costimulation17287217
GO:0038095TAS-Fc-epsilon receptor signaling pathway-
GO:0042100IEA-B cell proliferation-
GO:0042102IEA-positive regulation of T cell proliferation-
GO:0042981IEA-regulation of apoptotic process-
GO:0043123IEA-positive regulation of I-kappaB kinase/NF-kappaB signaling-
GO:0045061IEA-thymic T cell selection-
GO:0045086IEA-positive regulation of interleukin-2 biosynthetic process-
GO:0045577IEA-regulation of B cell differentiation-
GO:0045580IEA-regulation of T cell differentiation-
GO:0046037IEA-GMP metabolic process-
GO:0046710IEA-GDP metabolic process-
GO:0048872IEA-homeostasis of number of cells-
GO:0050852TAS-T cell receptor signaling pathway-
GO:0051092IMP-positive regulation of NF-kappaB transcription factor activity12154360
GO:0070970IEA-interleukin-2 secretion-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
CARD11PDPK111119615802604 Affinity Capture-Western
CARD11PDPK112407315802604 Affinity Capture-Western
CARD11BCL1011442911278692 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
CARD11BCL1012407311278692 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1916978
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-100219-1'