AutismKB 2.0

Annotation Details for DYRK3


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Basic Information Top
Gene Symbol:DYRK3 ( DYRK5,RED,REDK,hYAK3-2 )
Gene Full Name: dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
Band: 1q32.1
Quick LinksEntrez ID:8444; OMIM: 603497; Uniprot ID:DYRK3_HUMAN; ENSEMBL ID: ENSG00000143479; HGNC ID: 3094
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634IDA-nucleus10779429
GO:0005654IDA-nucleoplasm-
GO:0005737IDA-cytoplasm23415227
GO:0005829IDA-cytosol-
GO:0010494IDA-cytoplasmic stress granule23415227
GO:0043231IDA-intracellular membrane-bounded organelle-
GO ID Evidence Qualifier GO_term References
GO:0000287IDA-magnesium ion binding10779429
GO:0004672IDA-protein kinase activity10779429
GO:0004674IMP-protein serine/threonine kinase activity23415227
GO:0004712IEA-protein serine/threonine/tyrosine kinase activity-
GO:0004713IEA-protein tyrosine kinase activity-
GO:0005524IDA-ATP binding10779429
GO ID Evidence Qualifier GO_term References
GO:0006468IDA-protein phosphorylation10779429
GO:0018108IEA-peptidyl-tyrosine phosphorylation-
GO:0030218IDA-erythrocyte differentiation10779429
GO:0035617IMP-stress granule disassembly23415227
GO:0043066IEA-negative regulation of apoptotic process-
GO:0043518IEA-negative regulation of DNA damage response, signal transduction by p53 class mediator-
GO:0080135IMP-regulation of cellular response to stress23415227
GO:1903432IMP-regulation of TORC1 signaling23415227
Protein-Protein Interaction Top
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1330300
  • Data Attributes: MGI curated and HomoloGene calculated
No data
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  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018