AutismKB 2.0

Annotation Details for CASR


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Basic Information Top
Gene Symbol:CASR ( CAR,EIG8,FHH,FIH,GPRC2A,HHC,HHC1,MGC138441,NSHPT,PCAR1 )
Gene Full Name: calcium-sensing receptor
Band: 3q13.33-q21.1
Quick LinksEntrez ID:846; OMIM: 601199; Uniprot ID:CASR_HUMAN; ENSEMBL ID: ENSG00000036828; HGNC ID: 1514
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005886TAS-plasma membrane-
GO:0005887IDA-integral component of plasma membrane8702647
GO ID Evidence Qualifier GO_term References
GO:0004435TAS-phosphatidylinositol phospholipase C activity7874174
GO:0004930IDA-G-protein coupled receptor activity27434672
GO:0005509IDA-calcium ion binding27434672
GO:0005515IPI-protein binding20361938
GO:0016597IDA-amino acid binding27434672
GO:0042803IDA-protein homodimerization activity16740594
GO ID Evidence Qualifier GO_term References
GO:0001503TAS-ossification7874174
GO:0005513IDA-detection of calcium ion27434672
GO:0006874IDA-cellular calcium ion homeostasis27434672
GO:0007186IDA-G-protein coupled receptor signaling pathway27434672
GO:0007186IMP-G-protein coupled receptor signaling pathway8636323
GO:0007635TAS-chemosensory behavior7759551
GO:0009653TAS-anatomical structure morphogenesis7916660
GO:0070509IDA-calcium ion import20846291
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
CASRCASR1072969722601 Reconstituted Complex
FLNACASR10860511390379 11390380 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
FLNACASR10729611390379 11390380 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
RNF19ACASR11740516513638 Affinity Capture-Western
RNF19ACASR10729616513638 Affinity Capture-Western
UBCCASR11316416513638 Affinity Capture-Western
UBCCASR10729616513638 Affinity Capture-Western
VCPCASR11325816513638 Affinity Capture-Western
VCPCASR10729616513638 Affinity Capture-Western
CHD8CASR12170919151705 Affinity Capture-Western
CHD8CASR10729619151705 Affinity Capture-Western
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1351351
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-050119-8'