AutismKB 2.0

Annotation Details for SMARCA5


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:SMARCA5 ( ISWI,SNF2H,WCRF135,hISWI,hSNF2H )
Gene Full Name: SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5
Band: 4q31.21
Quick LinksEntrez ID:8467; OMIM: 603375; Uniprot ID:SMCA5_HUMAN; ENSEMBL ID: ENSG00000153147; HGNC ID: 11101
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0000793IDA-condensed chromosome12972596
GO:0001650IDA-fibrillar center-
GO:0005634IDA-nucleus12972596
GO:0005654TAS-nucleoplasm-
GO:0005677IEA-chromatin silencing complex-
GO:0016589IDA-NURF complex20850016
GO:0031213IPI-RSF complex9836642
GO:0043596IDAcolocalizes_withnuclear replication fork15543136
GO ID Evidence Qualifier GO_term References
GO:0003677IDA-DNA binding12972596
GO:0004386IEA-helicase activity-
GO:0005515IPI-protein binding10655480
GO:0005524IDA-ATP binding12972596
GO:0016887IDA-ATPase activity12972596
GO:0031491IEA-nucleosome binding-
GO:0042393IDAcontributes_tohistone binding12972596
GO ID Evidence Qualifier GO_term References
GO:0000183IEA-chromatin silencing at rDNA-
GO:0006302IEA-double-strand break repair-
GO:0006334IDA-nucleosome assembly12972596
GO:0006338IDA-chromatin remodeling9836642
GO:0006352IDA-DNA-templated transcription, initiation9836642
GO:0006357TAS-regulation of transcription from RNA polymerase II promoter9730600
GO:0016569IEA-covalent chromatin modification-
GO:0016584IDA-nucleosome positioning9836642
GO:0034080TAS-CENP-A containing nucleosome assembly-
GO:0043044IMP-ATP-dependent chromatin remodeling15543136
GO:0045815TAS-positive regulation of gene expression, epigenetic-
GO:0045893IEA-positive regulation of transcription, DNA-templated-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
SMARCA5CENPA10748715009096 Co-purification
SMARCA5CENPA11404515009096 Co-purification
SMARCA5CHD310753212198550 Co-purification
SMARCA5CHD311404512198550 Co-purification
SMARCA5CREB111404516675956 Affinity Capture-Western
SMARCA5CREB110777516675956 Affinity Capture-Western
SMARCA5CTNNB110788016510874 16510875 Affinity Capture-MS; Reconstituted Complex
SMARCA5CTNNB111404516510874 16510875 Affinity Capture-MS; Reconstituted Complex
SMARCA5DNMT110812315313181 Affinity Capture-Western
SMARCA5DNMT111404515313181 Affinity Capture-Western
SMARCA5DNMT3B10812615120635 15148359 Affinity Capture-Western; Co-purification; Reconstituted Complex
SMARCA5DNMT3B11404515120635 15148359 Affinity Capture-Western; Co-purification; Reconstituted Complex
SMARCA5HDAC210931612198550 15775975 Affinity Capture-Western; Co-localization; Co-purification
SMARCA5HDAC211404512198550 15775975 Affinity Capture-Western; Co-localization; Co-purification
SMARCA5MAF11026916675956 Affinity Capture-Western
SMARCA5MAF11404516675956 Affinity Capture-Western
SMARCA5MCM311404515775975 Co-localization
SMARCA5MCM311034015775975 Co-localization
SMARCA5MYO1C11072516514417 Affinity Capture-Western
SMARCA5MYO1C11404516514417 Affinity Capture-Western
SMARCA5RAD2111182212198550 Co-purification
SMARCA5RAD2111404512198550 Co-purification
SMARCA5RBBP411186312198550 Co-purification
SMARCA5RBBP411404512198550 Co-purification
SMARCA5SATB111221112374985 Reconstituted Complex
SMARCA5SATB111404512374985 Reconstituted Complex
SMARCA5USF111323717846119 Affinity Capture-MS
SMARCA5USF111404517846119 Affinity Capture-MS
SMARCA5SMC1A11387112198550 Co-purification
SMARCA5SMC1A11404512198550 Co-purification
SMARCA5HIST1H3A11394611691835 Affinity Capture-Western
SMARCA5HIST1H3A11404511691835 Affinity Capture-Western
SMARCA5HIST1H4A11395511691835 16917504 Affinity Capture-Western
SMARCA5HIST1H4A11404511691835 16917504 Affinity Capture-Western
BAZ1ASMARCA511634710655480 10880450 11980720 12198550 12374985 Affinity Capture-Western; Co-fractionation; Co-purification; Reconstituted Complex
BAZ1ASMARCA511404510655480 10880450 11980720 12198550 12374985 Affinity Capture-Western; Co-fractionation; Co-purification; Reconstituted Complex
POLE3SMARCA511990310880450 14759371 Affinity Capture-Western; Co-purification; Reconstituted Complex
POLE3SMARCA511404510880450 14759371 Affinity Capture-Western; Co-purification; Reconstituted Complex
CHRAC1SMARCA511990410880450 14759371 Affinity Capture-Western; Co-purification; Reconstituted Complex
CHRAC1SMARCA511404510880450 14759371 Affinity Capture-Western; Co-purification; Reconstituted Complex
BAZ2ASMARCA511634611532953 16085498 19578370 Affinity Capture-Western; Reconstituted Complex
BAZ2ASMARCA511404511532953 16085498 19578370 Affinity Capture-Western; Reconstituted Complex
HIST2H2ABSMARCA513046911691835 Affinity Capture-Western
HIST2H2ABSMARCA511404511691835 Affinity Capture-Western
BAZ1BSMARCA511449711980720 16603771 Affinity Capture-MS; Affinity Capture-Western; Co-fractionation
BAZ1BSMARCA511404511980720 16603771 Affinity Capture-MS; Affinity Capture-Western; Co-fractionation
SMC3SMARCA511457412198550 Co-purification
SMC3SMARCA511404512198550 Co-purification
CDT1SMARCA511404518162579 Affinity Capture-MS; Affinity Capture-Western; Reconstituted Complex
CDT1SMARCA512355518162579 Affinity Capture-MS; Affinity Capture-Western; Reconstituted Complex
RSF1SMARCA511972418519663 Affinity Capture-Western
RSF1SMARCA511404518519663 Affinity Capture-Western
SIN3ASMARCA511743918535655 Affinity Capture-Western
SIN3ASMARCA511404518535655 Affinity Capture-Western
Gene Symbol Interactant Interaction ID References Description
SMARCA5DNMT3B19382415120635 DNMT3B interacts with hSNF2H.
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1935129
  • Data Attributes: HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-021125-1'