AutismKB 2.0

Annotation Details for SORBS2


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Basic Information Top
Gene Symbol:SORBS2 ( ARGBP2,FLJ93447,KIAA0777,PRO0618 )
Gene Full Name: sorbin and SH3 domain containing 2
Band: 4q35.1
Quick LinksEntrez ID:8470; OMIM: NA; Uniprot ID:SRBS2_HUMAN; ENSEMBL ID: ENSG00000154556; HGNC ID: 24098
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634NAS-nucleus9211900
GO:0005925IEA-focal adhesion-
GO:0015629TAS-actin cytoskeleton9211900
GO:0016324IEA-apical plasma membrane-
GO:0030018NAS-Z disc9211900
GO:0030027IEA-lamellipodium-
GO:0048471IEA-perinuclear region of cytoplasm-
GO ID Evidence Qualifier GO_term References
GO:0003723IDA-RNA binding22658674
GO:0005200TAS-structural constituent of cytoskeleton9211900
GO:0005515IPI-protein binding15161933
GO:0008093TAS-cytoskeletal adaptor activity9211900
GO:0008307TAS-structural constituent of muscle9211900
GO ID Evidence Qualifier GO_term References
GO:0007015IEA-actin filament organization-
GO:0007155IEA-cell adhesion-
GO:0008150ND-biological_process-
GO:0016477IEA-cell migration-
GO:0061049ISS-cell growth involved in cardiac muscle cell development-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
SORBS2ABL11065439211900 12475393 Affinity Capture-Western; Biochemical Activity; Reconstituted Complex
SORBS2ABL11140479211900 12475393 Affinity Capture-Western; Biochemical Activity; Reconstituted Complex
SORBS2ABL21065459211900 Biochemical Activity; Reconstituted Complex; Two-hybrid
SORBS2ABL21140479211900 Biochemical Activity; Reconstituted Complex; Two-hybrid
SORBS2CBL11404712475393 15128873 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
SORBS2CBL10731512475393 15128873 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
SORBS2EGFR10827620029029 PCA
SORBS2EGFR11404720029029 PCA
SORBS2PTK2B10848015128873 Affinity Capture-Western; Reconstituted Complex
SORBS2PTK2B11404715128873 Affinity Capture-Western; Reconstituted Complex
SORBS2SFN10907215778465 Affinity Capture-MS
SORBS2SFN11404715778465 Affinity Capture-MS
SORBS2MLLT411044710521485 Reconstituted Complex
SORBS2MLLT411404710521485 Reconstituted Complex
SORBS2RPL911205316169070 Two-hybrid
SORBS2RPL911404716169070 Two-hybrid
SORBS2VCL11325710521485 Reconstituted Complex
SORBS2VCL11404710521485 Reconstituted Complex
SORBS2YWHAE11336316189514 Two-hybrid
SORBS2YWHAE11404716189514 Two-hybrid
DLGAP4SORBS211404710521485 Reconstituted Complex
DLGAP4SORBS211651310521485 Reconstituted Complex
DLGAP1SORBS211466010521485 Reconstituted Complex
DLGAP1SORBS211404710521485 Reconstituted Complex
FLOT1SORBS211404715128873 Affinity Capture-Western
FLOT1SORBS211550615128873 Affinity Capture-Western
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-070308-2'