AutismKB 2.0

Annotation Details for CDC42BPA


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Basic Information Top
Gene Symbol:CDC42BPA ( DKFZp686L1738,DKFZp686P1738,FLJ23347,KIAA0451,MRCK,MRCKA,PK428 )
Gene Full Name: CDC42 binding protein kinase alpha (DMPK-like)
Band: 1q42.13
Quick LinksEntrez ID:8476; OMIM: 603412; Uniprot ID:MRCKA_HUMAN; ENSEMBL ID: ENSG00000143776; HGNC ID: 1737
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005737IEA-cytoplasm-
GO:0005911ISS-cell-cell junction-
GO:0031252ISS-cell leading edge-
GO:0042641IDA-actomyosin18854160
GO:0070062IDA-extracellular exosome19056867
GO ID Evidence Qualifier GO_term References
GO:0000287IDA-magnesium ion binding9092543
GO:0004674IDA-protein serine/threonine kinase activity9092543
GO:0005515IPI-protein binding9418861
GO:0005524IDA-ATP binding9092543
GO:0042802IPI-identical protein binding11283256
GO ID Evidence Qualifier GO_term References
GO:0006468IDA-protein phosphorylation9092543
GO:0016477IMP-cell migration18854160
GO:0031032IMP-actomyosin structure organization18854160
GO:0031532IDA-actin cytoskeleton reorganization9418861
GO:0035556IEA-intracellular signal transduction-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
CDC42BPACDC4211405120936779 Two-hybrid
CDC42BPACDC4210743320936779 Two-hybrid
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:2441841
  • Data Attributes: HomoloGene calculated
No data
No data

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018