AutismKB 2.0

Annotation Details for PARP10


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Basic Information Top
Gene Symbol:PARP10 ( FLJ14464 )
Gene Full Name: poly (ADP-ribose) polymerase family, member 10
Band: 8q24.3
Quick LinksEntrez ID:84875; OMIM: 609564; Uniprot ID:PAR10_HUMAN; ENSEMBL ID: ENSG00000178685; HGNC ID: 25895
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634IDA-nucleus15674325
GO:0005730IDA-nucleolus-
GO:0005737IDA-cytoplasm15674325
GO:0005829IDA-cytosol-
GO:0005829TAS-cytosol-
GO:0043231IDA-intracellular membrane-bounded organelle-
GO ID Evidence Qualifier GO_term References
GO:0003950IMP-NAD+ ADP-ribosyltransferase activity23473667
GO:0003950TAS-NAD+ ADP-ribosyltransferase activity-
GO:0005515IPI-protein binding15674325
GO:0070530IMP-K63-linked polyubiquitin binding23575687
GO ID Evidence Qualifier GO_term References
GO:0006471IMP-protein ADP-ribosylation23575687
GO:0010629IMP-negative regulation of gene expression23575687
GO:0010847IDA-regulation of chromatin assembly15674325
GO:0032088IMP-negative regulation of NF-kappaB transcription factor activity23575687
GO:0033159IMP-negative regulation of protein import into nucleus, translocation23575687
GO:0034356TAS-NAD biosynthesis via nicotinamide riboside salvage pathway-
GO:0045071IMP-negative regulation of viral genome replication22176891
GO:0048147IDA-negative regulation of fibroblast proliferation15674325
GO:0070212IDA-protein poly-ADP-ribosylation15674325
GO:0070212IMP-protein poly-ADP-ribosylation23473667
GO:0070213IMP-protein auto-ADP-ribosylation23575687
GO:1900045IMP-negative regulation of protein K63-linked ubiquitination23575687
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
PARP10MYC12432015674325 Affinity Capture-Western; Reconstituted Complex
PARP10MYC11069415674325 Affinity Capture-Western; Reconstituted Complex
PARP10HIST2H2AC11393415674325 Biochemical Activity
PARP10HIST2H2AC12432015674325 Biochemical Activity
PARP10HIST2H2BE11394515674325 Biochemical Activity
PARP10HIST2H2BE12432015674325 Biochemical Activity
PARP10HIST1H3A12432015674325 Biochemical Activity
PARP10HIST1H3A11394615674325 Biochemical Activity
PARP10HIST1H4A12432015674325 Biochemical Activity
PARP10HIST1H4A11395515674325 Biochemical Activity
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:3712326
  • Data Attributes: MGI curated and HomoloGene calculated
No data
No data

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  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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