AutismKB 2.0

Annotation Details for PPP1R15B


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Basic Information Top
Gene Symbol:PPP1R15B ( CREP,FLJ14744 )
Gene Full Name: protein phosphatase 1, regulatory (inhibitor) subunit 15B
Band: 1q32.1
Quick LinksEntrez ID:84919; OMIM: 613257; Uniprot ID:PR15B_HUMAN; ENSEMBL ID: ENSG00000158615; HGNC ID: 14951
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0000164IDA-protein phosphatase type 1 complex26307080
GO:0000164ISS-protein phosphatase type 1 complex-
GO ID Evidence Qualifier GO_term References
GO:0005515IPI-protein binding15231748
GO:0019888IEA-protein phosphatase regulator activity-
GO ID Evidence Qualifier GO_term References
GO:0001933IMP-negative regulation of protein phosphorylation26307080
GO:0006983IEA-ER overload response-
GO:0042542IEA-response to hydrogen peroxide-
GO:0050790IEA-regulation of catalytic activity-
GO:0070262ISS-peptidyl-serine dephosphorylation-
GO:1903898TAS-negative regulation of PERK-mediated unfolded protein response22013210
GO:1903912ISS-negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation-
Protein-Protein Interaction Top
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:2444211
  • Data Attributes: MGI curated and HomoloGene calculated
No data
No data

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  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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