AutismKB 2.0

Annotation Details for PPM1D


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Basic Information Top
Gene Symbol:PPM1D ( PP2C-DELTA,WIP1 )
Gene Full Name: protein phosphatase, Mg2+/Mn2+ dependent, 1D
Band: 17q23.3
Quick LinksEntrez ID:8493; OMIM: 605100; Uniprot ID:PPM1D_HUMAN; ENSEMBL ID: ENSG00000170836; HGNC ID: 9277
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634TAS-nucleus9177166
GO ID Evidence Qualifier GO_term References
GO:0004722IDA-protein serine/threonine phosphatase activity20801214
GO:0005515IPI-protein binding17936559
GO:0046872IEA-metal ion binding-
GO:0051019IPI-mitogen-activated protein kinase binding21283629
GO ID Evidence Qualifier GO_term References
GO:0000086IEA-G2/M transition of mitotic cell cycle-
GO:0006470TAS-protein dephosphorylation9177166
GO:0008285TAS-negative regulation of cell proliferation9177166
GO:0009267IEA-cellular response to starvation-
GO:0009314TAS-response to radiation9177166
GO:0009617IEA-response to bacterium-
GO:0035970IDA-peptidyl-threonine dephosphorylation20801214
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
PPM1DCDC5L10742411101529 Affinity Capture-MS; Co-purification
PPM1DCDC5L11406511101529 Affinity Capture-MS; Co-purification
PPM1DH2AFX11406520101220 Biochemical Activity
PPM1DH2AFX10926820101220 Biochemical Activity
PPM1DMDM211406517936559 Affinity Capture-Western
PPM1DMDM211035817936559 Affinity Capture-Western
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1858214
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-040426-815'