AutismKB 2.0

Annotation Details for CYP4F2


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Basic Information Top
Gene Symbol:CYP4F2 ( CPF2 )
Gene Full Name: cytochrome P450, family 4, subfamily F, polypeptide 2
Band: 19p13.12
Quick LinksEntrez ID:8529; OMIM: 604426; Uniprot ID:CP4F2_HUMAN; ENSEMBL ID: ENSG00000186115; HGNC ID: 2645
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005737IDA-cytoplasm10660572
GO:0005789TAS-endoplasmic reticulum membrane20861217
GO:0016324IDA-apical plasma membrane10660572
GO:0031090IEA-organelle membrane-
GO:0043231IDA-intracellular membrane-bounded organelle9618440
GO ID Evidence Qualifier GO_term References
GO:0004497TAS-monooxygenase activity-
GO:0005506IEA-iron ion binding-
GO:0005515IPI-protein binding17474147
GO:0008392IDA-arachidonic acid epoxygenase activity9618440
GO:0016709IDA-oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen19297519
GO:0018685IDA-alkane 1-monooxygenase activity18433732
GO:0020037IEA-heme binding-
GO:0050051IDA-leukotriene-B4 20-monooxygenase activity8026587
GO:0050051TAS-leukotriene-B4 20-monooxygenase activity-
GO:0052869IDA-arachidonic acid omega-hydroxylase activity9618440
GO:0052871IDA-alpha-tocopherol omega-hydroxylase activity20861217
GO:0052872IDA-tocotrienol omega-hydroxylase activity20861217
GO:0097258TAS-20-hydroxy-leukotriene B4 omega oxidase activity-
GO:0097259TAS-20-aldehyde-leukotriene B4 20-monooxygenase activity-
GO ID Evidence Qualifier GO_term References
GO:0000038IDA-very long-chain fatty acid metabolic process18433732
GO:0001676IDA-long-chain fatty acid metabolic process18433732
GO:0003091IEP-renal water homeostasis10660572
GO:0003095IEP-pressure natriuresis10660572
GO:0006690TAS-icosanoid metabolic process-
GO:0006691TAS-leukotriene metabolic process-
GO:0007596TAS-blood coagulation19297519
GO:0008217IMP-regulation of blood pressure18391101
GO:0017144IMP-drug metabolic process21084764
GO:0019369IDA-arachidonic acid metabolic process10660572
GO:0019373IDA-epoxygenase P450 pathway9618440
GO:0032304IMP-negative regulation of icosanoid secretion18391101
GO:0032305IMP-positive regulation of icosanoid secretion17341693
GO:0036101IDA-leukotriene B4 catabolic process8026587
GO:0042360IDA-vitamin E metabolic process20861217
GO:0042361IDA-menaquinone catabolic process24138531
GO:0042376IDA-phylloquinone catabolic process24138531
GO:0042376IEA-phylloquinone catabolic process-
GO:0042377IDA-vitamin K catabolic process19297519
GO:0055078IEP-sodium ion homeostasis10660572
GO:0055114IDA-oxidation-reduction process9618440
GO:0097267TAS-omega-hydroxylase P450 pathway-
Protein-Protein Interaction Top
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:2158641
  • Data Attributes: HomoloGene calculated
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Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018