AutismKB 2.0

Annotation Details for DOCK7


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Basic Information Top
Gene Symbol:DOCK7 ( KIAA1771,ZIR2 )
Gene Full Name: dedicator of cytokinesis 7
Band: 1p31.3
Quick LinksEntrez ID:85440; OMIM: NA; Uniprot ID:DOCK7_HUMAN; ENSEMBL ID: ENSG00000116641; HGNC ID: 19190
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005925IDA-focal adhesion21423176
GO:0008180IDAcolocalizes_withCOP9 signalosome18850735
GO:0030424TAS-axon16982419
GO:0030426TAS-growth cone16982419
GO:0043005TAS-neuron projection16982419
GO:0045178TAS-basal part of cell16982419
GO ID Evidence Qualifier GO_term References
GO:0005085IEA-guanyl-nucleotide exchange factor activity-
GO:0048365IDA-Rac GTPase binding16982419
GO ID Evidence Qualifier GO_term References
GO:0000226IMP-microtubule cytoskeleton organization16982419
GO:0007264IEA-small GTPase mediated signal transduction-
GO:0007409IMP-axonogenesis16982419
GO:0022027ISS-interkinetic nuclear migration-
GO:0031175IMP-neuron projection development16982419
GO:0033138IMP-positive regulation of peptidyl-serine phosphorylation16982419
GO:0045200IMP-establishment of neuroblast polarity16982419
GO:0050767ISS-regulation of neurogenesis-
GO:0090630IDA-activation of GTPase activity16982419
GO:1904754IMP-positive regulation of vascular associated smooth muscle cell migration22158624
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
DOCK7GTF2A110921217643375 Affinity Capture-MS
DOCK7GTF2A112452717643375 Affinity Capture-MS
DOCK7MLH111043817148452 Affinity Capture-MS
DOCK7MLH112452717148452 Affinity Capture-MS
DOCK7TSC111309915963462 Affinity Capture-MS
DOCK7TSC112452715963462 Affinity Capture-MS
DOCK7USP711362219615732 Affinity Capture-MS
DOCK7USP712452719615732 Affinity Capture-MS
DOCK7USP1911607819615732 Affinity Capture-MS
DOCK7USP1912452719615732 Affinity Capture-MS
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1914549
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-050302-15'