Annotation Details for PIAS1


Gene Symbol: | PIAS1 ( DDXBP1,GBP,GU/RH-II,MGC141878,MGC141879,ZMIZ3 ) |
---|---|
Gene Full Name: | protein inhibitor of activated STAT, 1 |
Band: | 15q23 |
Quick Links | Entrez ID:8554; OMIM: 603566; Uniprot ID:PIAS1_HUMAN; ENSEMBL ID: ENSG00000033800; HGNC ID: 2752 |
Relate to Another Database: | SFARIGene; denovo-db |
GO ID | Evidence | Qualifier | GO_term | References |
---|---|---|---|---|
GO:0005634 | IDA | - | nucleus | 14752048 |
GO:0005654 | TAS | - | nucleoplasm | - |
GO:0016605 | ISS | colocalizes_with | PML body | - |
GO:0016607 | IEA | - | nuclear speck | - |
GO ID | Evidence | Qualifier | GO_term | References |
---|---|---|---|---|
GO:0003677 | IEA | - | DNA binding | - |
GO:0003713 | NAS | - | transcription coactivator activity | 15572661 |
GO:0003714 | TAS | - | transcription corepressor activity | 10805787 |
GO:0005515 | IPI | - | protein binding | 14752048 |
GO:0008022 | IEA | - | protein C-terminus binding | - |
GO:0008134 | IEA | - | transcription factor binding | - |
GO:0008270 | IEA | - | zinc ion binding | - |
GO:0016874 | IEA | - | ligase activity | - |
GO:0019789 | EXP | - | SUMO transferase activity | 12356736 |
GO:0019899 | IPI | - | enzyme binding | 17087506 |
GO:0019904 | IEA | - | protein domain specific binding | - |
GO:0031625 | IEA | - | ubiquitin protein ligase binding | - |
GO:0050681 | NAS | - | androgen receptor binding | 15572661 |
GO:0061665 | IDA | - | SUMO ligase activity | 18579533 |
GO ID | Evidence | Qualifier | GO_term | References |
---|---|---|---|---|
GO:0000082 | IEA | - | G1/S transition of mitotic cell cycle | - |
GO:0000122 | IEA | - | negative regulation of transcription from RNA polymerase II promoter | - |
GO:0006351 | IEA | - | transcription, DNA-templated | - |
GO:0007259 | TAS | - | JAK-STAT cascade | 10805787 |
GO:0007283 | IEA | - | spermatogenesis | - |
GO:0008542 | IEA | - | visual learning | - |
GO:0016925 | IDA | - | protein sumoylation | 18579533 |
GO:0016925 | IEA | - | protein sumoylation | - |
GO:0016925 | ISS | - | protein sumoylation | - |
GO:0016925 | TAS | - | protein sumoylation | - |
GO:0030521 | NAS | - | androgen receptor signaling pathway | 15572661 |
GO:0032436 | ISS | - | positive regulation of proteasomal ubiquitin-dependent protein catabolic process | - |
GO:0033235 | IDA | - | positive regulation of protein sumoylation | 17696781 |
GO:0042127 | ISS | - | regulation of cell proliferation | - |
GO:0043066 | IEA | - | negative regulation of apoptotic process | - |
GO:0045444 | IEA | - | fat cell differentiation | - |
GO:0045893 | NAS | - | positive regulation of transcription, DNA-templated | 15572661 |
GO:0051152 | IEA | - | positive regulation of smooth muscle cell differentiation | - |
GO:0060334 | TAS | - | regulation of interferon-gamma-mediated signaling pathway | - |
GO:0065004 | IEA | - | protein-DNA complex assembly | - |
Gene Symbol | Interactant | Interaction ID | References | Description |
---|---|---|---|---|
PIAS1 | AKT1 | 114124 | 17533377 | Two-hybrid |
PIAS1 | AKT1 | 106710 | 17533377 | Two-hybrid |
PIAS1 | AR | 106862 | 11117529 | Two-hybrid |
PIAS1 | AR | 114124 | 11117529 | Two-hybrid |
PIAS1 | BRCA1 | 107140 | 20016594 20016603 | Biochemical Activity; Co-localization |
PIAS1 | BRCA1 | 114124 | 20016594 20016603 | Biochemical Activity; Co-localization |
PIAS1 | CREB1 | 114124 | 20936779 | Two-hybrid |
PIAS1 | CREB1 | 107775 | 20936779 | Two-hybrid |
PIAS1 | CSRP2 | 114124 | 11672422 | Two-hybrid |
PIAS1 | CSRP2 | 107848 | 11672422 | Two-hybrid |
PIAS1 | DNMT3A | 114124 | 14752048 | Affinity Capture-Western; Reconstituted Complex; Two-hybrid |
PIAS1 | DNMT3A | 108125 | 14752048 | Affinity Capture-Western; Reconstituted Complex; Two-hybrid |
PIAS1 | GLUL | 114124 | 20936779 | Two-hybrid |
PIAS1 | GLUL | 109014 | 20936779 | Two-hybrid |
PIAS1 | JUN | 109928 | 11867732 | Reconstituted Complex |
PIAS1 | JUN | 114124 | 11867732 | Reconstituted Complex |
PIAS1 | MBD1 | 110322 | 17066076 19074829 | Affinity Capture-Western; Reconstituted Complex; Two-hybrid |
PIAS1 | MBD1 | 114124 | 17066076 19074829 | Affinity Capture-Western; Reconstituted Complex; Two-hybrid |
PIAS1 | MITF | 114124 | 16029420 | Reconstituted Complex |
PIAS1 | MITF | 110432 | 16029420 | Reconstituted Complex |
PIAS1 | MX1 | 110684 | 11716541 | Two-hybrid |
PIAS1 | MX1 | 114124 | 11716541 | Two-hybrid |
PIAS1 | PPARG | 114124 | 16127449 | Affinity Capture-Western; Co-localization |
PIAS1 | PPARG | 111464 | 16127449 | Affinity Capture-Western; Co-localization |
PIAS1 | TRIM27 | 114124 | 15907835 | Affinity Capture-Western; Two-hybrid |
PIAS1 | TRIM27 | 111919 | 15907835 | Affinity Capture-Western; Two-hybrid |
PIAS1 | SIAH1 | 112372 | 17533377 | Reconstituted Complex; Two-hybrid |
PIAS1 | SIAH1 | 114124 | 17533377 | Reconstituted Complex; Two-hybrid |
PIAS1 | SIAH2 | 114124 | 17533377 | Affinity Capture-Western; Biochemical Activity; Reconstituted Complex; Two-hybrid |
PIAS1 | SIAH2 | 112373 | 17533377 | Affinity Capture-Western; Biochemical Activity; Reconstituted Complex; Two-hybrid |
PIAS1 | SUMO3 | 114124 | 20016603 | Co-localization |
PIAS1 | SUMO3 | 112496 | 20016603 | Co-localization |
PIAS1 | SUMO2 | 114124 | 18806873 19394292 20016603 | Affinity Capture-MS; Co-localization; Reconstituted Complex |
PIAS1 | SUMO2 | 112497 | 18806873 19394292 20016603 | Affinity Capture-MS; Co-localization; Reconstituted Complex |
PIAS1 | SP3 | 114124 | 12356736 | Reconstituted Complex; Two-hybrid |
PIAS1 | SP3 | 112553 | 12356736 | Reconstituted Complex; Two-hybrid |
PIAS1 | SREBF2 | 112599 | 20936779 | Two-hybrid |
PIAS1 | SREBF2 | 114124 | 20936779 | Two-hybrid |
PIAS1 | STAT1 | 114124 | 10805787 | Reconstituted Complex; Two-hybrid |
PIAS1 | STAT1 | 112649 | 10805787 | Reconstituted Complex; Two-hybrid |
PIAS1 | TP53 | 114124 | 10380882 11583632 11867732 | Biochemical Activity; Reconstituted Complex; Two-hybrid |
PIAS1 | TP53 | 113010 | 10380882 11583632 11867732 | Biochemical Activity; Reconstituted Complex; Two-hybrid |
PIAS1 | UBE2I | 114124 | 11583632 12356736 14609633 20936779 | Reconstituted Complex; Two-hybrid |
PIAS1 | UBE2I | 113177 | 11583632 12356736 14609633 20936779 | Reconstituted Complex; Two-hybrid |
PIAS1 | SUMO1 | 113188 | 11583632 14609633 | Two-hybrid |
PIAS1 | SUMO1 | 114124 | 11583632 14609633 | Two-hybrid |
PIAS1 | ZNF76 | 114124 | 15280358 | Affinity Capture-Western; Two-hybrid |
PIAS1 | ZNF76 | 113448 | 15280358 | Affinity Capture-Western; Two-hybrid |
STAB2 | PIAS1 | 114124 | 14701874 | Affinity Capture-Western |
STAB2 | PIAS1 | 120727 | 14701874 | Affinity Capture-Western |
NCOR1 | PIAS1 | 114124 | 16421255 | Affinity Capture-Western; Reconstituted Complex; Two-hybrid |
NCOR1 | PIAS1 | 114973 | 16421255 | Affinity Capture-Western; Reconstituted Complex; Two-hybrid |
ZMIZ2 | PIAS1 | 114124 | 20159969 | Affinity Capture-Western |
ZMIZ2 | PIAS1 | 123701 | 20159969 | Affinity Capture-Western |
No data |
No data |