AutismKB 2.0

Annotation Details for TCAP


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Basic Information Top
Gene Symbol:TCAP ( CMD1N,LGMD2G,T-cap,TELE,telethonin )
Gene Full Name: titin-cap (telethonin)
Band: 17q12
Quick LinksEntrez ID:8557; OMIM: 604488; Uniprot ID:TELT_HUMAN; ENSEMBL ID: ENSG00000173991; HGNC ID: 11610
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005829TAS-cytosol-
GO:0030018IDA-Z disc9817758
GO:0031674ISS-I band-
GO ID Evidence Qualifier GO_term References
GO:0005515IPI-protein binding10984498
GO:0008307IMP-structural constituent of muscle9817758
GO:0030674IDA-protein binding, bridging15582318
GO:0031432IPI-titin binding9817758
GO:0036122IPI-BMP binding17921333
GO:0044325IPI-ion channel binding11697903
GO:0051373IPI-FATZ binding15582318
GO:0070080IPI-titin Z domain binding11846417
GO ID Evidence Qualifier GO_term References
GO:0001756IEA-somitogenesis-
GO:0003009IEP-skeletal muscle contraction9817758
GO:0003300IMP-cardiac muscle hypertrophy15582318
GO:0006461TAS-protein complex assembly9817758
GO:0007512IMP-adult heart development9817758
GO:0014898IMP-cardiac muscle hypertrophy in response to stress12507422
GO:0030049TAS-muscle filament sliding-
GO:0030240IMP-skeletal muscle thin filament assembly9817758
GO:0030241IMP-skeletal muscle myosin thick filament assembly9817758
GO:0030916IEA-otic vesicle formation-
GO:0035994TAS-response to muscle stretch17921333
GO:0035995IMP-detection of muscle stretch12507422
GO:0045214IMP-sarcomere organization9817758
GO:0045214TAS-sarcomere organization17921333
GO:0048739IMP-cardiac muscle fiber development9817758
GO:0048769IMP-sarcomerogenesis9817758
GO:0050982TAS-detection of mechanical stimulus17921333
GO:0055003IMP-cardiac myofibril assembly9817758
GO:0055008IMP-cardiac muscle tissue morphogenesis9817758
GO:0060048IMP-cardiac muscle contraction12507422
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
TCAPTTN1141279645487 9804419 9817758 12446666 Biochemical Activity; Co-purification; Reconstituted Complex; Two-hybrid
TCAPTTN1131249645487 9804419 9817758 12446666 Biochemical Activity; Co-purification; Reconstituted Complex; Two-hybrid
MYOZ1TCAP11412710984498 11842093 Affinity Capture-Western; Reconstituted Complex
MYOZ1TCAP12184910984498 11842093 Affinity Capture-Western; Reconstituted Complex
MYOZ2TCAP11972611842093 Affinity Capture-Western
MYOZ2TCAP11412711842093 Affinity Capture-Western
MYOZ3TCAP12489911842093 Affinity Capture-Western
MYOZ3TCAP11412711842093 Affinity Capture-Western
ANKRD2TCAP11412715136035 Affinity Capture-Western; Reconstituted Complex
ANKRD2TCAP11766915136035 Affinity Capture-Western; Reconstituted Complex
TRIM63TCAP11412715967462 Two-hybrid
TRIM63TCAP12419515967462 Two-hybrid
Gene Symbol Interactant Interaction ID References Description
TCAPTTN25761415802564 Titin interacts with telethonin. This interaction was modelled on a demonstrated interaction between human Titin and telethonin from unspecified species.
TRIM55TCAP31243415967462 MURF-2 interacts with T-cap.
MYOZ1TCAP18235610984498 FATZ interacts with TELE.
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1330233
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-070501-5'