Annotation Details for PRKRA
Basic Information Top
| Gene Symbol: | PRKRA ( DYT16,PACT,RAX ) |
|---|---|
| Gene Full Name: | protein kinase, interferon-inducible double stranded RNA dependent activator |
| Band: | 2q31.2 |
| Quick Links | Entrez ID:8575; OMIM: 603424; Uniprot ID:PRKRA_HUMAN; ENSEMBL ID: ENSG00000180228; HGNC ID: 9438 |
| Relate to Another Database: | SFARIGene; denovo-db |
| GO ID | Evidence | Qualifier | GO_term | References |
|---|---|---|---|---|
| GO:0005654 | IDA | - | nucleoplasm | - |
| GO:0005737 | IDA | - | cytoplasm | 17452327 |
| GO:0005829 | IDA | - | cytosol | - |
| GO:0005829 | TAS | - | cytosol | - |
| GO:0016020 | IDA | - | membrane | 19946888 |
| GO:0048471 | IEA | - | perinuclear region of cytoplasm | - |
| GO:0070578 | IDA | - | RISC-loading complex | 23661684 |
| GO ID | Evidence | Qualifier | GO_term | References |
|---|---|---|---|---|
| GO:0003723 | IDA | - | RNA binding | 22681889 |
| GO:0003725 | IDA | - | double-stranded RNA binding | 23661684 |
| GO:0005515 | IPI | - | protein binding | 16424907 |
| GO:0008047 | IEA | - | enzyme activator activity | - |
| GO:0019899 | IPI | - | enzyme binding | 23661684 |
| GO:0042802 | IPI | - | identical protein binding | 16169070 |
| GO:0042803 | IPI | - | protein homodimerization activity | 17452327 |
| GO ID | Evidence | Qualifier | GO_term | References |
|---|---|---|---|---|
| GO:0006468 | IEA | - | protein phosphorylation | - |
| GO:0006955 | TAS | - | immune response | 9687506 |
| GO:0008285 | TAS | - | negative regulation of cell proliferation | 9687506 |
| GO:0009615 | TAS | - | response to virus | 9687506 |
| GO:0010586 | TAS | - | miRNA metabolic process | - |
| GO:0030422 | IDA | - | production of siRNA involved in RNA interference | 17452327 |
| GO:0030422 | TAS | - | production of siRNA involved in RNA interference | - |
| GO:0031054 | IDA | - | pre-miRNA processing | 16424907 |
| GO:0034599 | IEA | - | cellular response to oxidative stress | - |
| GO:0035196 | IDA | - | production of miRNAs involved in gene silencing by miRNA | 23661684 |
| GO:0042473 | IEA | - | outer ear morphogenesis | - |
| GO:0042474 | IEA | - | middle ear morphogenesis | - |
| GO:0043085 | IEA | - | positive regulation of catalytic activity | - |
| GO:0048705 | IEA | - | skeletal system morphogenesis | - |
| GO:0050821 | IMP | - | protein stabilization | 16424907 |
| GO:2001244 | IEA | - | positive regulation of intrinsic apoptotic signaling pathway | - |
| Gene Symbol | Interactant | Interaction ID | References | Description |
|---|---|---|---|---|
| PRKRA | GDF9 | 114143 | 16169070 | Two-hybrid |
| PRKRA | GDF9 | 108930 | 16169070 | Two-hybrid |
| PRKRA | EIF2AK2 | 114143 | 9687506 11985496 | Affinity Capture-Western; Phenotypic Enhancement; Reconstituted Complex; Two-hybrid |
| PRKRA | EIF2AK2 | 111596 | 9687506 11985496 | Affinity Capture-Western; Phenotypic Enhancement; Reconstituted Complex; Two-hybrid |
| PRKRA | PRPSAP1 | 111618 | 17353931 | Affinity Capture-MS |
| PRKRA | PRPSAP1 | 114143 | 17353931 | Affinity Capture-MS |
| PRKRA | RB1 | 114143 | 9010216 | Affinity Capture-Western; Reconstituted Complex |
| PRKRA | RB1 | 111860 | 9010216 | Affinity Capture-Western; Reconstituted Complex |
| PRKRA | TP53 | 113010 | 9010216 | Affinity Capture-Western; Reconstituted Complex |
| PRKRA | TP53 | 114143 | 9010216 | Affinity Capture-Western; Reconstituted Complex |
| COPS6 | PRKRA | 114143 | 16169070 | Two-hybrid |
| COPS6 | PRKRA | 116176 | 16169070 | Two-hybrid |
| PRKRA | PRKRA | 114143 | 16169070 | Two-hybrid |
| SETDB1 | PRKRA | 115202 | 16169070 | Two-hybrid |
| SETDB1 | PRKRA | 114143 | 16169070 | Two-hybrid |
| SYNCRIP | PRKRA | 115755 | 17353931 | Affinity Capture-MS |
| SYNCRIP | PRKRA | 114143 | 17353931 | Affinity Capture-MS |
| IGF2BP1 | PRKRA | 114143 | 17353931 | Affinity Capture-MS |
| IGF2BP1 | PRKRA | 115886 | 17353931 | Affinity Capture-MS |
| RPL36 | PRKRA | 117388 | 17353931 | Affinity Capture-MS |
| RPL36 | PRKRA | 114143 | 17353931 | Affinity Capture-MS |
| No data |
| No data |
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