Annotation Details for RUNX3


Gene Symbol: | RUNX3 ( AML2,CBFA3,FLJ34510,MGC16070,PEBP2aC ) |
---|---|
Gene Full Name: | runt-related transcription factor 3 |
Band: | 1p36.11 |
Quick Links | Entrez ID:864; OMIM: 600210; Uniprot ID:RUNX3_HUMAN; ENSEMBL ID: ENSG00000020633; HGNC ID: 10473 |
Relate to Another Database: | SFARIGene; denovo-db |
GO ID | Evidence | Qualifier | GO_term | References |
---|---|---|---|---|
GO:0000790 | ISS | - | nuclear chromatin | - |
GO:0005634 | IDA | - | nucleus | 20100835 |
GO:0005654 | TAS | - | nucleoplasm | - |
GO:0005730 | IDA | - | nucleolus | - |
GO:0005737 | IDA | - | cytoplasm | 20100835 |
GO:0005829 | IDA | - | cytosol | - |
GO:0005829 | TAS | - | cytosol | - |
GO:0043231 | IDA | - | intracellular membrane-bounded organelle | - |
GO ID | Evidence | Qualifier | GO_term | References |
---|---|---|---|---|
GO:0000977 | ISS | - | RNA polymerase II regulatory region sequence-specific DNA binding | - |
GO:0000981 | IBA | - | RNA polymerase II transcription factor activity, sequence-specific DNA binding | - |
GO:0000981 | ISS | - | RNA polymerase II transcription factor activity, sequence-specific DNA binding | - |
GO:0003700 | TAS | - | transcription factor activity, sequence-specific DNA binding | 7607690 |
GO:0005515 | IPI | - | protein binding | 9751710 |
GO:0005524 | NAS | - | ATP binding | 7835892 |
GO ID | Evidence | Qualifier | GO_term | References |
---|---|---|---|---|
GO:0000122 | ISS | - | negative regulation of transcription from RNA polymerase II promoter | - |
GO:0001503 | IBA | - | ossification | - |
GO:0002062 | IBA | - | chondrocyte differentiation | - |
GO:0006355 | NAS | - | regulation of transcription, DNA-templated | 7622058 |
GO:0006357 | IBA | - | regulation of transcription from RNA polymerase II promoter | - |
GO:0006366 | TAS | - | transcription from RNA polymerase II promoter | 7607690 |
GO:0006468 | IDA | - | protein phosphorylation | 20100835 |
GO:0030097 | IBA | - | hemopoiesis | - |
GO:0045595 | IBA | - | regulation of cell differentiation | - |
GO:0045786 | ISS | - | negative regulation of cell cycle | - |
GO:0045893 | IDA | - | positive regulation of transcription, DNA-templated | 20599712 |
GO:0048935 | TAS | - | peripheral nervous system neuron development | 20096094 |
GO:0050680 | ISS | - | negative regulation of epithelial cell proliferation | - |
GO:0071559 | IDA | - | response to transforming growth factor beta | 20599712 |
Gene Symbol | Interactant | Interaction ID | References | Description |
---|---|---|---|---|
TLE1 | RUNX3 | 112943 | 9751710 | Far Western; Two-hybrid |
TLE1 | RUNX3 | 107312 | 9751710 | Far Western; Two-hybrid |
YAP1 | RUNX3 | 107312 | 10228168 | Reconstituted Complex |
YAP1 | RUNX3 | 115684 | 10228168 | Reconstituted Complex |
SMAD1 | RUNX3 | 110261 | 10531362 | Affinity Capture-Western |
SMAD1 | RUNX3 | 107312 | 10531362 | Affinity Capture-Western |
SMAD2 | RUNX3 | 110262 | 10531362 | Affinity Capture-Western |
SMAD2 | RUNX3 | 107312 | 10531362 | Affinity Capture-Western |
SMAD3 | RUNX3 | 110263 | 10531362 15138260 | Affinity Capture-Western |
SMAD3 | RUNX3 | 107312 | 10531362 15138260 | Affinity Capture-Western |
SMAD5 | RUNX3 | 110265 | 10531362 | Affinity Capture-Western |
SMAD5 | RUNX3 | 107312 | 10531362 | Affinity Capture-Western |
EP300 | RUNX3 | 108347 | 15138260 | Affinity Capture-Western |
EP300 | RUNX3 | 107312 | 15138260 | Affinity Capture-Western |
SMURF1 | RUNX3 | 121411 | 15138260 | Affinity Capture-Western |
SMURF1 | RUNX3 | 107312 | 15138260 | Affinity Capture-Western |
SMURF2 | RUNX3 | 122265 | 15138260 | Affinity Capture-Western |
SMURF2 | RUNX3 | 107312 | 15138260 | Affinity Capture-Western |
UBC | RUNX3 | 113164 | 15138260 | Affinity Capture-Western |
UBC | RUNX3 | 107312 | 15138260 | Affinity Capture-Western |
CBFB | RUNX3 | 107313 | 15138260 | Affinity Capture-Western |
CBFB | RUNX3 | 107312 | 15138260 | Affinity Capture-Western |
HDAC9 | RUNX3 | 107312 | 15138260 | Affinity Capture-Western |
HDAC9 | RUNX3 | 115083 | 15138260 | Affinity Capture-Western |
SUV39H1 | RUNX3 | 107312 | 16652147 | Affinity Capture-Western |
SUV39H1 | RUNX3 | 112706 | 16652147 | Affinity Capture-Western |
PHB2 | RUNX3 | 107312 | 17353931 | Affinity Capture-MS |
PHB2 | RUNX3 | 116459 | 17353931 | Affinity Capture-MS |
SP110 | RUNX3 | 109657 | 20211142 | Two-hybrid |
SP110 | RUNX3 | 107312 | 20211142 | Two-hybrid |
No data |
No data |
- MGI ID: MGI:102672
- Data Attributes: MGI curated and HomoloGene calculated
- ZFIN ID: ZDB-GENE-000605-2