AutismKB 2.0

Annotation Details for PTCH2


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Basic Information Top
Gene Symbol:PTCH2 ( PTC2 )
Gene Full Name: patched 2
Band: 1p34.1
Quick LinksEntrez ID:8643; OMIM: 603673; Uniprot ID:PTC2_HUMAN; ENSEMBL ID: ENSG00000117425; HGNC ID: 9586
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0016021IEA-integral component of membrane-
GO ID Evidence Qualifier GO_term References
GO:0005119IPI-smoothened binding9811851
GO:0008158TAS-hedgehog receptor activity11001584
GO:0097108IPI-hedgehog family protein binding9811851
GO:0097108TAS-hedgehog family protein binding11001584
GO ID Evidence Qualifier GO_term References
GO:0001709IEA-cell fate determination-
GO:0007165IEA-signal transduction-
GO:0009957IEA-epidermal cell fate specification-
GO:0042633IEA-hair cycle-
GO:0043588IEA-skin development-
GO:0045606IEA-positive regulation of epidermal cell differentiation-
GO:0045879TAS-negative regulation of smoothened signaling pathway11001584
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
PTCH2SMO1124929811851 Affinity Capture-Western
PTCH2SMO1141959811851 Affinity Capture-Western
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1095405
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-980526-44'