Gene Symbol:	PDE5A ( CGB-PDE,CN5A,PDE5 )
Gene Full Name:	phosphodiesterase 5A, cGMP-specific
Band:	4q26
Quick Links	Entrez ID:8654; OMIM: 603310; Uniprot ID:PDE5A_HUMAN; ENSEMBL ID: ENSG00000138735; HGNC ID: 8784
Relate to Another Database:	SFARIGene; denovo-db

GO ID	Evidence	Qualifier	GO_term	References
GO:0004114	NAS	-	3',5'-cyclic-nucleotide phosphodiesterase activity	9714779
GO:0030553	TAS	-	cGMP binding	15938621
GO:0046872	IEA	-	metal ion binding	-
GO:0047555	TAS	-	3',5'-cyclic-GMP phosphodiesterase activity	-

GO ID	Evidence	Qualifier	GO_term	References
GO:0007165	IEA	-	signal transduction	-
GO:0010613	IEA	-	positive regulation of cardiac muscle hypertrophy	-
GO:0030823	IEA	-	regulation of cGMP metabolic process	-
GO:0042130	IEA	-	negative regulation of T cell proliferation	-
GO:0043406	IEA	-	positive regulation of MAP kinase activity	-
GO:0046069	IDA	-	cGMP catabolic process	14687666
GO:0046069	IEA	-	cGMP catabolic process	-
GO:0055118	IEA	-	negative regulation of cardiac muscle contraction	-
GO:0055119	IEA	-	relaxation of cardiac muscle	-
GO:0060282	IEA	-	positive regulation of oocyte development	-

AutismKB 2.0

Annotation Details for PDE5A