AutismKB 2.0

Annotation Details for PDE5A


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Basic Information Top
Gene Symbol:PDE5A ( CGB-PDE,CN5A,PDE5 )
Gene Full Name: phosphodiesterase 5A, cGMP-specific
Band: 4q26
Quick LinksEntrez ID:8654; OMIM: 603310; Uniprot ID:PDE5A_HUMAN; ENSEMBL ID: ENSG00000138735; HGNC ID: 8784
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005575ND-cellular_component-
GO:0005829TAS-cytosol-
GO ID Evidence Qualifier GO_term References
GO:0004114NAS-3',5'-cyclic-nucleotide phosphodiesterase activity9714779
GO:0030553TAS-cGMP binding15938621
GO:0046872IEA-metal ion binding-
GO:0047555TAS-3',5'-cyclic-GMP phosphodiesterase activity-
GO ID Evidence Qualifier GO_term References
GO:0007165IEA-signal transduction-
GO:0010613IEA-positive regulation of cardiac muscle hypertrophy-
GO:0030823IEA-regulation of cGMP metabolic process-
GO:0042130IEA-negative regulation of T cell proliferation-
GO:0043406IEA-positive regulation of MAP kinase activity-
GO:0046069IDA-cGMP catabolic process14687666
GO:0046069IEA-cGMP catabolic process-
GO:0055118IEA-negative regulation of cardiac muscle contraction-
GO:0055119IEA-relaxation of cardiac muscle-
GO:0060282IEA-positive regulation of oocyte development-
Protein-Protein Interaction Top
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:2651499
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-060824-4'