Gene Symbol:	EIF3A ( EIF3,EIF3S10,KIAA0139,P167,TIF32,eIF3-p170,eIF3-theta,p180,p185 )
Gene Full Name:	eukaryotic translation initiation factor 3, subunit A
Band:	10q26.11
Quick Links	Entrez ID:8661; OMIM: 602039; Uniprot ID:EIF3A_HUMAN; ENSEMBL ID: ENSG00000107581; HGNC ID: 3271
Relate to Another Database:	SFARIGene; denovo-db

GO ID	Evidence	Qualifier	GO_term	References
GO:0005634	IDA	-	nucleus	-
GO:0005730	IDA	-	nucleolus	-
GO:0005737	NAS	-	cytoplasm	9150439
GO:0005829	IDA	-	cytosol	-
GO:0005829	TAS	-	cytosol	-
GO:0005852	IDA	-	eukaryotic translation initiation factor 3 complex	17322308
GO:0005874	IEA	-	microtubule	-
GO:0016020	IDA	-	membrane	19946888
GO:0043614	IBA	-	multi-eIF complex	-
GO:0071540	IBA	-	eukaryotic translation initiation factor 3 complex, eIF3e	-
GO:0071541	IBA	-	eukaryotic translation initiation factor 3 complex, eIF3m	-

GO ID	Evidence	Qualifier	GO_term	References
GO:0003723	IDA	-	RNA binding	22658674
GO:0003729	IBA	-	mRNA binding	-
GO:0003743	IC	contributes_to	translation initiation factor activity	17322308
GO:0003743	IDA	contributes_to	translation initiation factor activity	17581632
GO:0005198	NAS	-	structural molecule activity	9150439
GO:0005515	IPI	-	protein binding	11169732
GO:0030971	IEA	-	receptor tyrosine kinase binding	-

GO ID	Evidence	Qualifier	GO_term	References
GO:0001732	IDA	-	formation of cytoplasmic translation initiation complex	17581632
GO:0002188	IBA	-	translation reinitiation	-
GO:0006413	IC	-	translational initiation	17322308
GO:0006413	TAS	-	translational initiation	-
GO:0070373	IEA	-	negative regulation of ERK1 and ERK2 cascade	-
GO:0075522	IDA	-	IRES-dependent viral translational initiation	9573242
GO:0075525	IDA	-	viral translational termination-reinitiation	21347434

Gene Symbol	Interactant	Interaction ID	References	Description
EIF3A	EIF4A1	114210	17353931	Affinity Capture-MS
EIF3A	EIF4A1	108289	17353931	Affinity Capture-MS
EIF3A	EIF4A2	114210	17353931	Affinity Capture-MS
EIF3A	EIF4A2	108290	17353931	Affinity Capture-MS
EIF3A	EIF4B	114210	8816444	Affinity Capture-Western; Far Western
EIF3A	EIF4B	108291	8816444	Affinity Capture-Western; Far Western
EIF3A	EIF4G1	114210	16541103	Affinity Capture-Western
EIF3A	EIF4G1	108296	16541103	Affinity Capture-Western
EIF3A	EIF4G2	108297	9418880 10611228	Affinity Capture-Western
EIF3A	EIF4G2	114210	9418880 10611228	Affinity Capture-Western
EIF3A	EIF3E	114210	11590142 14519125 17353931	Affinity Capture-MS; Affinity Capture-Western; Co-purification
EIF3A	EIF3E	109857	11590142 14519125 17353931	Affinity Capture-MS; Affinity Capture-Western; Co-purification
EIF3A	MCC	114210	17353931	Affinity Capture-MS
EIF3A	MCC	110333	17353931	Affinity Capture-MS
EIF3A	PIK3C2A	114210	20562859	Affinity Capture-MS
EIF3A	PIK3C2A	111304	20562859	Affinity Capture-MS
EIF3A	TFE3	114210	17353931	Affinity Capture-MS
EIF3A	TFE3	112888	17353931	Affinity Capture-MS
EIF3A	UBC	114210	18354498	Affinity Capture-Western
EIF3A	UBC	113164	18354498	Affinity Capture-Western
EIF3A	YWHAZ	113366	20936779	Two-hybrid
EIF3A	YWHAZ	114210	20936779	Two-hybrid
EIF3I	EIF3A	114210	8995409 14519125 17353931	Affinity Capture-MS; Affinity Capture-Western; Co-purification
EIF3I	EIF3A	114217	8995409 14519125 17353931	Affinity Capture-MS; Affinity Capture-Western; Co-purification
EIF3B	EIF3A	114211	8995410 9822659 14519125 16541103	Affinity Capture-Western; Co-purification; Far Western
EIF3B	EIF3A	114210	8995410 9822659 14519125 16541103	Affinity Capture-Western; Co-purification; Far Western
EIF3D	EIF3A	114213	9822659 14519125 17353931	Affinity Capture-MS; Affinity Capture-Western; Co-purification
EIF3D	EIF3A	114210	9822659 14519125 17353931	Affinity Capture-MS; Affinity Capture-Western; Co-purification
EIF3F	EIF3A	114210	9822659 14519125 17353931 19615732	Affinity Capture-MS; Affinity Capture-Western; Co-purification
EIF3F	EIF3A	114214	9822659 14519125 17353931 19615732	Affinity Capture-MS; Affinity Capture-Western; Co-purification
EIF3H	EIF3A	114210	9822659 14519125 17353931 19615732	Affinity Capture-MS; Affinity Capture-Western; Co-purification
EIF3H	EIF3A	114216	9822659 14519125 17353931 19615732	Affinity Capture-MS; Affinity Capture-Western; Co-purification
EIF3C	EIF3A	114212	9822659 14519125	Affinity Capture-Western; Co-purification
EIF3C	EIF3A	114210	9822659 14519125	Affinity Capture-Western; Co-purification
EIF3J	EIF3A	114210	9822659 14519125	Affinity Capture-Western; Co-purification
EIF3J	EIF3A	114218	9822659 14519125	Affinity Capture-Western; Co-purification
EIF3G	EIF3A	114210	9822659 14519125	Affinity Capture-Western; Co-purification; Far Western
EIF3G	EIF3A	114215	9822659 14519125	Affinity Capture-Western; Co-purification; Far Western
EIF3L	EIF3A	114210	11590142 17353931	Affinity Capture-MS; Affinity Capture-Western; Co-fractionation
EIF3L	EIF3A	119516	11590142 17353931	Affinity Capture-MS; Affinity Capture-Western; Co-fractionation
DISC1	EIF3A	114210	12812986	Affinity Capture-Western; Two-hybrid
DISC1	EIF3A	118061	12812986	Affinity Capture-Western; Two-hybrid
EIF3K	EIF3A	114210	14519125 17353931	Affinity Capture-MS; Co-purification
EIF3K	EIF3A	118148	14519125 17353931	Affinity Capture-MS; Co-purification
EIF1B	EIF3A	115578	17353931	Affinity Capture-MS
EIF1B	EIF3A	114210	17353931	Affinity Capture-MS
EIF3M	EIF3A	115743	17353931	Affinity Capture-MS
EIF3M	EIF3A	114210	17353931	Affinity Capture-MS
FBXO32	EIF3A	114210	18354498	Affinity Capture-Western; Reconstituted Complex
FBXO32	EIF3A	125395	18354498	Affinity Capture-Western; Reconstituted Complex
WDR48	EIF3A	114210	19615732	Affinity Capture-MS
WDR48	EIF3A	121649	19615732	Affinity Capture-MS
USP3	EIF3A	114210	19615732	Affinity Capture-MS
USP3	EIF3A	115285	19615732	Affinity Capture-MS
PRKAG2	EIF3A	114210	20562859	Affinity Capture-MS
PRKAG2	EIF3A	119531	20562859	Affinity Capture-MS
UBA5	EIF3A	114210	20562859	Affinity Capture-MS
UBA5	EIF3A	122964	20562859	Affinity Capture-MS

AutismKB 2.0

Annotation Details for EIF3A

Simple Query:

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics