AutismKB 2.0

Annotation Details for VAMP8


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Basic Information Top
Gene Symbol:VAMP8 ( EDB,VAMP-8 )
Gene Full Name: vesicle-associated membrane protein 8 (endobrevin)
Band: 2p11.2
Quick LinksEntrez ID:8673; OMIM: 603177; Uniprot ID:VAMP8_HUMAN; ENSEMBL ID: ENSG00000118640; HGNC ID: 12647
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005737IDA-cytoplasm18253931
GO:0005765IDA-lysosomal membrane23217709
GO:0005769TAS-early endosome9614193
GO:0005829IDA-cytosol22589474
GO:0005886IDA-plasma membrane18253931
GO:0005886TAS-plasma membrane-
GO:0016020IDA-membrane16677249
GO:0016021IEA-integral component of membrane-
GO:0030665TAS-clathrin-coated vesicle membrane-
GO:0030667IDA-secretory granule membrane16677249
GO:0030667TAS-secretory granule membrane-
GO:0030670TAS-phagocytic vesicle membrane-
GO:0031201IDA-SNARE complex12130530
GO:0031901IEA-early endosome membrane-
GO:0031902IDA-late endosome membrane23217709
GO:0031982IDA-vesicle18570918
GO:0035577IDA-azurophil granule membrane16677249
GO:0035577TAS-azurophil granule membrane-
GO:0035579TAS-specific granule membrane-
GO:0048471IDA-perinuclear region of cytoplasm18570918
GO:0055037IDA-recycling endosome18570918
GO:0055038TAS-recycling endosome membrane-
GO:0070062IDA-extracellular exosome19056867
GO:0070821TAS-tertiary granule membrane-
GO:0098594IDA-mucin granule22144578
GO ID Evidence Qualifier GO_term References
GO:0000149IBA-SNARE binding-
GO:0005484IBA-SNAP receptor activity-
GO:0005515IPI-protein binding23217709
GO:0019869IDA-chloride channel inhibitor activity18570918
GO ID Evidence Qualifier GO_term References
GO:0002479TAS-antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent-
GO:0006892TAS-post-Golgi vesicle-mediated transport-
GO:0006906IBA-vesicle fusion-
GO:0015031IEA-protein transport-
GO:0016240IDA-autophagosome docking25686604
GO:0043308IMPNOTeosinophil degranulation16677249
GO:0043312IMPNOTneutrophil degranulation16677249
GO:0043312TAS-neutrophil degranulation-
GO:0046718IMP-viral entry into host cell24550300
GO:0061024TAS-membrane organization-
GO:0065009IEA-regulation of molecular function-
GO:0070254IMP-mucus secretion22144578
GO:0097352IMP-autophagosome maturation23217709
GO:1903076IDA-regulation of protein localization to plasma membrane18570918
GO:1903531IDA-negative regulation of secretion by cell12130530
GO:1903595IMP-positive regulation of histamine secretion by mast cell18253931
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
VAMP8STX211422112828989 Affinity Capture-Western
VAMP8STX210836812828989 Affinity Capture-Western
VAMP8STX1A11422111112705 Affinity Capture-Western; Reconstituted Complex
VAMP8STX1A11267611112705 Affinity Capture-Western; Reconstituted Complex
VAMP8STX411267910820264 12130530 Affinity Capture-MS; Affinity Capture-Western
VAMP8STX411422110820264 12130530 Affinity Capture-MS; Affinity Capture-Western
VAMP8VAMP211422112130530 Reconstituted Complex
VAMP8VAMP211271112130530 Reconstituted Complex
VAMP8STX711422111101518 11278762 Affinity Capture-MS; Affinity Capture-Western; Co-purification
VAMP8STX711400311101518 11278762 Affinity Capture-MS; Affinity Capture-Western; Co-purification
NAPAVAMP81142219614193 Reconstituted Complex
NAPAVAMP81143059614193 Reconstituted Complex
SNAP23VAMP811430310820264 12828989 Affinity Capture-Western
SNAP23VAMP811422110820264 12828989 Affinity Capture-Western
VTI1AVAMP812678911101518 Affinity Capture-Western; Co-purification
VTI1AVAMP811422111101518 Affinity Capture-Western; Co-purification
STX8VAMP811486711101518 Affinity Capture-Western; Co-purification
STX8VAMP811422111101518 Affinity Capture-Western; Co-purification
STX6VAMP811552211839770 Affinity Capture-Western
STX6VAMP811422111839770 Affinity Capture-Western
VAMP3VAMP811474712130530 Reconstituted Complex
VAMP3VAMP811422112130530 Reconstituted Complex
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1336882
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-030131-5215'