AutismKB 2.0

Annotation Details for TNFRSF25


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:TNFRSF25 ( APO-3,DDR3,DR3,LARD,TNFRSF12,TR3,TRAMP,WSL-1,WSL-LR )
Gene Full Name: tumor necrosis factor receptor superfamily, member 25
Band: 1p36.31
Quick LinksEntrez ID:8718; OMIM: 603366; Uniprot ID:TNR25_HUMAN; ENSEMBL ID: ENSG00000215788; HGNC ID: 11910
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005576IEA-extracellular region-
GO:0005829NAS-cytosol9114039
GO:0005886IDA-plasma membrane11911831
GO:0005886TAS-plasma membrane-
GO:0005887TAS-integral component of plasma membrane9052839
GO ID Evidence Qualifier GO_term References
GO:0004872NAS-receptor activity9114039
GO:0005031TAS-tumor necrosis factor-activated receptor activity9052839
GO ID Evidence Qualifier GO_term References
GO:0006915NAS-apoptotic process9114039
GO:0006954IBA-inflammatory response-
GO:0006955IBA-immune response-
GO:0007165TAS-signal transduction8875942
GO:0007166TAS-cell surface receptor signaling pathway9052839
GO:0007275IBA-multicellular organism development-
GO:0032496IBA-response to lipopolysaccharide-
GO:0033209TAS-tumor necrosis factor-mediated signaling pathway-
GO:0042127IBA-regulation of cell proliferation-
GO:0042981IBA-regulation of apoptotic process-
GO:0042981NAS-regulation of apoptotic process9114039
GO:0097190TAS-apoptotic signaling pathway8994832
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
TNFRSF25DAP311358711376335 Reconstituted Complex
TNFRSF25DAP311425811376335 Reconstituted Complex
TNFRSF25TRADD1142578934525 Affinity Capture-Western; Two-hybrid
TNFRSF25TRADD1142588934525 Affinity Capture-Western; Two-hybrid
TNFRSF25TNFRSF251142588934525 Two-hybrid
NOL3TNFRSF251142589560245 Phenotypic Suppression
NOL3TNFRSF251144779560245 Phenotypic Suppression
BAG4TNFRSF251142589915703 Affinity Capture-Western
BAG4TNFRSF251149069915703 Affinity Capture-Western
TNFSF15TNFRSF2511425811911831 Affinity Capture-Western
TNFSF15TNFRSF2511529111911831 Affinity Capture-Western
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1934667
  • Data Attributes: MGI curated and HomoloGene calculated
No data
No data

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved