Gene Symbol:	GBF1 ( ARF1GEF,FLJ21263,FLJ21500,KIAA0248,MGC134877,MGC134878 )
Gene Full Name:	golgi brefeldin A resistant guanine nucleotide exchange factor 1
Band:	10q24.32
Quick Links	Entrez ID:8729; OMIM: 603698; Uniprot ID:GBF1_HUMAN; ENSEMBL ID: ENSG00000107862; HGNC ID: 4181
Relate to Another Database:	SFARIGene; denovo-db

GO ID	Evidence	Qualifier	GO_term	References
GO:0000139	TAS	-	Golgi membrane	-
GO:0005739	IEA	-	mitochondrion	-
GO:0005777	IEA	-	peroxisome	-
GO:0005788	IEA	-	endoplasmic reticulum lumen	-
GO:0005793	IDA	-	endoplasmic reticulum-Golgi intermediate compartment	12047556
GO:0005794	IDA	-	Golgi apparatus	-
GO:0005795	IEA	-	Golgi stack	-
GO:0005801	IDA	-	cis-Golgi network	12047556
GO:0005802	IDA	-	trans-Golgi network	23386609
GO:0005811	IEA	-	lipid particle	-
GO:0005829	TAS	-	cytosol	-
GO:0016020	IDA	-	membrane	19946888
GO:0031252	IDA	-	cell leading edge	22573891

GO ID	Evidence	Qualifier	GO_term	References
GO:0005085	TAS	-	guanyl-nucleotide exchange factor activity	-
GO:0005086	IBA	-	ARF guanyl-nucleotide exchange factor activity	-
GO:0005086	TAS	-	ARF guanyl-nucleotide exchange factor activity	-
GO:0005515	IPI	-	protein binding	17956946
GO:0005547	IDA	-	phosphatidylinositol-3,4,5-trisphosphate binding	22573891
GO:0080025	IDA	-	phosphatidylinositol-3,5-bisphosphate binding	22573891

GO ID	Evidence	Qualifier	GO_term	References
GO:0002263	IMP	-	cell activation involved in immune response	22573891
GO:0006888	TAS	-	ER to Golgi vesicle-mediated transport	-
GO:0006890	IMP	-	retrograde vesicle-mediated transport, Golgi to ER	12047556
GO:0006890	TAS	-	retrograde vesicle-mediated transport, Golgi to ER	-
GO:0006892	TAS	-	post-Golgi vesicle-mediated transport	-
GO:0006895	IMP	-	Golgi to endosome transport	23386609
GO:0007030	IMP	-	Golgi organization	12808027
GO:0007346	IMP	-	regulation of mitotic cell cycle	23418352
GO:0015031	IEA	-	protein transport	-
GO:0030593	IMP	-	neutrophil chemotaxis	22573891
GO:0032012	IEA	-	regulation of ARF protein signal transduction	-
GO:0034067	IMP	-	protein localization to Golgi apparatus	17956946
GO:0042147	IMP	-	retrograde transport, endosome to Golgi	12808027
GO:0043547	IEA	-	positive regulation of GTPase activity	-
GO:0048205	IMP	-	COPI coating of Golgi vesicle	12047556
GO:0061162	IMP	-	establishment of monopolar cell polarity	22573891
GO:0070973	IMP	-	protein localization to endoplasmic reticulum exit site	17956946
GO:0090166	IMP	-	Golgi disassembly	23418352
GO:0097111	IMP	-	endoplasmic reticulum-Golgi intermediate compartment organization	17956946
GO:0098586	IMP	-	cellular response to virus	28389568
GO:1903409	IMP	-	reactive oxygen species biosynthetic process	22573891
GO:1903420	IMP	-	protein localization to endoplasmic reticulum tubular network	17956946
GO:2000008	IMP	-	regulation of protein localization to cell surface	17956946

Gene Symbol	Interactant	Interaction ID	References	Description
GBF1	YWHAG	114268	17353931	Affinity Capture-MS
GBF1	YWHAG	113364	17353931	Affinity Capture-MS
COPG	GBF1	114268	19039328	Affinity Capture-Western
COPG	GBF1	116496	19039328	Affinity Capture-Western
KBTBD7	GBF1	123873	20562859	Affinity Capture-MS
KBTBD7	GBF1	114268	20562859	Affinity Capture-MS

AutismKB 2.0

Annotation Details for GBF1