AutismKB 2.0

Annotation Details for CBS


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Basic Information Top
Gene Symbol:CBS ( HIP4 )
Gene Full Name: cystathionine-beta-synthase
Band: 21q22.3
Quick LinksEntrez ID:875; OMIM: 613381; Uniprot ID:CBS_HUMAN; ENSEMBL ID: ENSG00000160200; HGNC ID: 1550
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634IDA-nucleus17087506
GO:0005737IDA-cytoplasm23981774
GO:0005829IDA-cytosol16780588
GO:0005829TAS-cytosol-
GO ID Evidence Qualifier GO_term References
GO:0004122IDA-cystathionine beta-synthase activity7929220
GO:0004122TAS-cystathionine beta-synthase activity-
GO:0005515IPI-protein binding17087506
GO:0019825IDA-oxygen binding24515102
GO:0019899IPI-enzyme binding17087506
GO:0020037IDA-heme binding7929220
GO:0020037IMP-heme binding18776696
GO:0030170IDA-pyridoxal phosphate binding7929220
GO:0031625IPI-ubiquitin protein ligase binding17087506
GO:0042802IPI-identical protein binding16189514
GO:0042803IDA-protein homodimerization activity11483494
GO:0046872IEA-metal ion binding-
GO:0050421IDA-nitrite reductase (NO-forming) activity24416422
GO:0070025IDA-carbon monoxide binding24515102
GO:0070026IDA-nitric oxide binding24416422
GO:0072341IDA-modified amino acid binding20031578
GO:1904047IDA-S-adenosyl-L-methionine binding22985361
GO ID Evidence Qualifier GO_term References
GO:0006535IEA-cysteine biosynthetic process from serine-
GO:0006563IDA-L-serine metabolic process19010420
GO:0006565IDA-L-serine catabolic process18776696
GO:0019343IEA-cysteine biosynthetic process via cystathionine-
GO:0019344IDA-cysteine biosynthetic process24416422
GO:0019346TAS-transsulfuration-
GO:0019448IDA-L-cysteine catabolic process15520012
GO:0042262IMP-DNA protection24534463
GO:0043418IDA-homocysteine catabolic process18776696
GO:0050667IDA-homocysteine metabolic process19010420
GO:0055114IEA-oxidation-reduction process-
GO:0070814IDA-hydrogen sulfide biosynthetic process15520012
GO:0070814ISS-hydrogen sulfide biosynthetic process-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
CBSCBS10732111173483 11483494 16189514 Affinity Capture-Western; Co-crystal Structure; Two-hybrid
C17orf28CBS12972016189514 Two-hybrid
C17orf28CBS10732116189514 Two-hybrid
VTA1CBS11959516189514 Two-hybrid
VTA1CBS10732116189514 Two-hybrid
FXR2CBS11489016189514 Two-hybrid
FXR2CBS10732116189514 Two-hybrid
HGSCBS10732119019082 Reconstituted Complex
HGSCBS11459319019082 Reconstituted Complex
No data
No data
AlzGene, PDGene and SZGene Top
Gene Symbol Poly Names Gene overview in AlzGene
CBSCBS_31bpVNTR, CBS_844ins68, rs12329790 Gene overview in AlzGene
No data
Gene Symbol Poly Names Gene overview in SZGene
CBSrs72058776 Gene overview in SZGene
Animal Model Top
  • MGI ID: MGI:88285
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-021030-3'