AutismKB 2.0

Annotation Details for ADAM9


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Basic Information Top
Gene Symbol:ADAM9 ( CORD9,KIAA0021,MCMP,MDC9,Mltng )
Gene Full Name: ADAM metallopeptidase domain 9
Band: 8p11.22
Quick LinksEntrez ID:8754; OMIM: 602713; Uniprot ID:ADAM9_HUMAN; ENSEMBL ID: ENSG00000168615; HGNC ID: 216
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005615ISS-extracellular space8647900
GO:0005925IDA-focal adhesion21423176
GO:0009986ISS-cell surface8647900
GO:0016021IEA-integral component of membrane-
GO:0016323IEA-basolateral plasma membrane-
GO:0031233ISS-intrinsic component of external side of plasma membrane8647900
GO:0070062IDA-extracellular exosome23533145
GO ID Evidence Qualifier GO_term References
GO:0004222IDA-metalloendopeptidase activity9920899
GO:0004222IMP-metalloendopeptidase activity22480688
GO:0005080ISS-protein kinase C binding8647900
GO:0005178IC-integrin binding11162558
GO:0005178IDA-integrin binding15361064
GO:0005178IPI-integrin binding17704059
GO:0005515IPI-protein binding10527948
GO:0005518IMP-collagen binding15361064
GO:0008237IMP-metallopeptidase activity12535668
GO:0017124IPI-SH3 domain binding10531379
GO:0017124ISS-SH3 domain binding8647900
GO:0043236IMP-laminin binding15361064
GO:0046872IEA-metal ion binding-
GO ID Evidence Qualifier GO_term References
GO:0000186IDA-activation of MAPKK activity17704059
GO:0006509IDA-membrane protein ectodomain proteolysis9920899
GO:0006509IMP-membrane protein ectodomain proteolysis22480688
GO:0007155IMP-cell adhesion11162558
GO:0007160IMP-cell-matrix adhesion15361064
GO:0007179IMP-transforming growth factor beta receptor signaling pathway11955914
GO:0007179ISS-transforming growth factor beta receptor signaling pathway8647900
GO:0007229IC-integrin-mediated signaling pathway11162558
GO:0010042IMP-response to manganese ion11162558
GO:0016477ISS-cell migration-
GO:0030216IEP-keratinocyte differentiation17704059
GO:0033627IMP-cell adhesion mediated by integrin17704059
GO:0033627ISS-cell adhesion mediated by integrin-
GO:0033630IMP-positive regulation of cell adhesion mediated by integrin11162558
GO:0033631IEP-cell-cell adhesion mediated by integrin17704059
GO:0034241IMP-positive regulation of macrophage fusion11831872
GO:0034612IDA-response to tumor necrosis factor11831872
GO:0034616IEA-response to laminar fluid shear stress-
GO:0042117IMP-monocyte activation11831872
GO:0042542IMP-response to hydrogen peroxide17018608
GO:0050714IDA-positive regulation of protein secretion17704059
GO:0051044ISS-positive regulation of membrane protein ectodomain proteolysis8647900
GO:0051088TAS-PMA-inducible membrane protein ectodomain proteolysis9920899
GO:0051384ISS-response to glucocorticoid8647900
GO:0051549IMP-positive regulation of keratinocyte migration17704059
GO:0051592IMP-response to calcium ion11162558
GO:0071222IMP-cellular response to lipopolysaccharide22480688
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
ADAM9CDH111429016336960 Affinity Capture-Western
ADAM9CDH110743416336960 Affinity Capture-Western
ADAM9PRKCD1115669857183 Affinity Capture-Western
ADAM9PRKCD1142909857183 Affinity Capture-Western
ADAM9SH3GL211235310531379 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
ADAM9SH3GL211429010531379 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
MAD2L2ADAM911429010527948 Reconstituted Complex; Two-hybrid
MAD2L2ADAM911572210527948 Reconstituted Complex; Two-hybrid
SNX9ADAM911953510531379 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
SNX9ADAM911429010531379 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
Gene Symbol Interactant Interaction ID References Description
SH3D19ADAM918343915280379 An unspecified isoform of ADAM9 binds to Eve-1d.
No data
AlzGene, PDGene and SZGene Top
Gene Symbol Poly Names Gene overview in AlzGene
ADAM9rs10105311, rs6991968, rs7006414, rs7840270 Gene overview in AlzGene
No data
No data
Animal Model Top
  • MGI ID: MGI:105376
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-040912-127'