Annotation Details for ADAM9


Gene Symbol: | ADAM9 ( CORD9,KIAA0021,MCMP,MDC9,Mltng ) |
---|---|
Gene Full Name: | ADAM metallopeptidase domain 9 |
Band: | 8p11.22 |
Quick Links | Entrez ID:8754; OMIM: 602713; Uniprot ID:ADAM9_HUMAN; ENSEMBL ID: ENSG00000168615; HGNC ID: 216 |
Relate to Another Database: | SFARIGene; denovo-db |
GO ID | Evidence | Qualifier | GO_term | References |
---|---|---|---|---|
GO:0005615 | ISS | - | extracellular space | 8647900 |
GO:0005925 | IDA | - | focal adhesion | 21423176 |
GO:0009986 | ISS | - | cell surface | 8647900 |
GO:0016021 | IEA | - | integral component of membrane | - |
GO:0016323 | IEA | - | basolateral plasma membrane | - |
GO:0031233 | ISS | - | intrinsic component of external side of plasma membrane | 8647900 |
GO:0070062 | IDA | - | extracellular exosome | 23533145 |
GO ID | Evidence | Qualifier | GO_term | References |
---|---|---|---|---|
GO:0004222 | IDA | - | metalloendopeptidase activity | 9920899 |
GO:0004222 | IMP | - | metalloendopeptidase activity | 22480688 |
GO:0005080 | ISS | - | protein kinase C binding | 8647900 |
GO:0005178 | IC | - | integrin binding | 11162558 |
GO:0005178 | IDA | - | integrin binding | 15361064 |
GO:0005178 | IPI | - | integrin binding | 17704059 |
GO:0005515 | IPI | - | protein binding | 10527948 |
GO:0005518 | IMP | - | collagen binding | 15361064 |
GO:0008237 | IMP | - | metallopeptidase activity | 12535668 |
GO:0017124 | IPI | - | SH3 domain binding | 10531379 |
GO:0017124 | ISS | - | SH3 domain binding | 8647900 |
GO:0043236 | IMP | - | laminin binding | 15361064 |
GO:0046872 | IEA | - | metal ion binding | - |
GO ID | Evidence | Qualifier | GO_term | References |
---|---|---|---|---|
GO:0000186 | IDA | - | activation of MAPKK activity | 17704059 |
GO:0006509 | IDA | - | membrane protein ectodomain proteolysis | 9920899 |
GO:0006509 | IMP | - | membrane protein ectodomain proteolysis | 22480688 |
GO:0007155 | IMP | - | cell adhesion | 11162558 |
GO:0007160 | IMP | - | cell-matrix adhesion | 15361064 |
GO:0007179 | IMP | - | transforming growth factor beta receptor signaling pathway | 11955914 |
GO:0007179 | ISS | - | transforming growth factor beta receptor signaling pathway | 8647900 |
GO:0007229 | IC | - | integrin-mediated signaling pathway | 11162558 |
GO:0010042 | IMP | - | response to manganese ion | 11162558 |
GO:0016477 | ISS | - | cell migration | - |
GO:0030216 | IEP | - | keratinocyte differentiation | 17704059 |
GO:0033627 | IMP | - | cell adhesion mediated by integrin | 17704059 |
GO:0033627 | ISS | - | cell adhesion mediated by integrin | - |
GO:0033630 | IMP | - | positive regulation of cell adhesion mediated by integrin | 11162558 |
GO:0033631 | IEP | - | cell-cell adhesion mediated by integrin | 17704059 |
GO:0034241 | IMP | - | positive regulation of macrophage fusion | 11831872 |
GO:0034612 | IDA | - | response to tumor necrosis factor | 11831872 |
GO:0034616 | IEA | - | response to laminar fluid shear stress | - |
GO:0042117 | IMP | - | monocyte activation | 11831872 |
GO:0042542 | IMP | - | response to hydrogen peroxide | 17018608 |
GO:0050714 | IDA | - | positive regulation of protein secretion | 17704059 |
GO:0051044 | ISS | - | positive regulation of membrane protein ectodomain proteolysis | 8647900 |
GO:0051088 | TAS | - | PMA-inducible membrane protein ectodomain proteolysis | 9920899 |
GO:0051384 | ISS | - | response to glucocorticoid | 8647900 |
GO:0051549 | IMP | - | positive regulation of keratinocyte migration | 17704059 |
GO:0051592 | IMP | - | response to calcium ion | 11162558 |
GO:0071222 | IMP | - | cellular response to lipopolysaccharide | 22480688 |
Gene Symbol | Interactant | Interaction ID | References | Description |
---|---|---|---|---|
ADAM9 | CDH1 | 114290 | 16336960 | Affinity Capture-Western |
ADAM9 | CDH1 | 107434 | 16336960 | Affinity Capture-Western |
ADAM9 | PRKCD | 111566 | 9857183 | Affinity Capture-Western |
ADAM9 | PRKCD | 114290 | 9857183 | Affinity Capture-Western |
ADAM9 | SH3GL2 | 112353 | 10531379 | Affinity Capture-Western; Reconstituted Complex; Two-hybrid |
ADAM9 | SH3GL2 | 114290 | 10531379 | Affinity Capture-Western; Reconstituted Complex; Two-hybrid |
MAD2L2 | ADAM9 | 114290 | 10527948 | Reconstituted Complex; Two-hybrid |
MAD2L2 | ADAM9 | 115722 | 10527948 | Reconstituted Complex; Two-hybrid |
SNX9 | ADAM9 | 119535 | 10531379 | Affinity Capture-Western; Reconstituted Complex; Two-hybrid |
SNX9 | ADAM9 | 114290 | 10531379 | Affinity Capture-Western; Reconstituted Complex; Two-hybrid |
Gene Symbol | Interactant | Interaction ID | References | Description |
---|---|---|---|---|
SH3D19 | ADAM9 | 183439 | 15280379 | An unspecified isoform of ADAM9 binds to Eve-1d. |
No data |
Gene Symbol | Poly Names | Gene overview in AlzGene |
---|---|---|
ADAM9 | rs10105311, rs6991968, rs7006414, rs7840270 | Gene overview in AlzGene |
No data |
No data |
- MGI ID: MGI:105376
- Data Attributes: MGI curated and HomoloGene calculated
- ZFIN ID: ZDB-GENE-040912-127