AutismKB 2.0

Annotation Details for TNFRSF10B


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Basic Information Top
Gene Symbol:TNFRSF10B ( CD262,DR5,KILLER,KILLER/DR5,TRAIL-R2,TRAILR2,TRICK2,TRICK2A,TRICK2B,TRICKB,ZTNFR9 )
Gene Full Name: tumor necrosis factor receptor superfamily, member 10b
Band: 8p21.3
Quick LinksEntrez ID:8795; OMIM: 603612; Uniprot ID:TR10B_HUMAN; ENSEMBL ID: ENSG00000120889; HGNC ID: 11905
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005622IEA-intracellular-
GO:0005886TAS-plasma membrane-
GO:0005887IBA-integral component of plasma membrane-
GO:0009986IDA-cell surface22952982
GO:0016021IC-integral component of membrane9311998
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
TNFRSF10BFAS10685115659383 Co-purification
TNFRSF10BFAS11432315659383 Co-purification
TNFRSF10BFASLG11432315659383 Co-purification
TNFRSF10BFASLG10685215659383 Co-purification
TNFRSF10BRHOA11432315659383 Co-purification
TNFRSF10BRHOA10688015659383 Co-purification
TNFRSF10BARHGDIA10688915659383 Co-purification
TNFRSF10BARHGDIA11432315659383 Co-purification
TNFRSF10BBID11432315659383 Co-purification
TNFRSF10BBID10710615659383 Co-purification
TNFRSF10BCASP81143239325248 11940602 15659383 Affinity Capture-Western; Co-purification
TNFRSF10BCASP81072919325248 11940602 15659383 Affinity Capture-Western; Co-purification
TNFRSF10BCASP101143239325248 15659383 Affinity Capture-Western; Co-purification
TNFRSF10BCASP101072939325248 15659383 Affinity Capture-Western; Co-purification
TNFRSF10BMSN11432315659383 Co-purification
TNFRSF10BMSN11058415659383 Co-purification
TNFRSF10BMAPK811158515659383 Co-purification
TNFRSF10BMAPK811432315659383 Co-purification
TNFRSF10BTNFRSF1A11298615659383 Co-purification
TNFRSF10BTNFRSF1A11432315659383 Co-purification
TNFRSF10BEZR11432315659383 Co-purification
TNFRSF10BEZR11327115659383 Co-purification
TNFRSF10BTRADD1142579430227 Affinity Capture-Western
TNFRSF10BTRADD1143239430227 Affinity Capture-Western
TNFRSF10BRIPK11142749430227 Affinity Capture-Western
TNFRSF10BRIPK11143239430227 Affinity Capture-Western
TNFRSF10BTNFSF101142809311998 10549288 11094155 Affinity Capture-MS; Co-crystal Structure; Reconstituted Complex
TNFRSF10BTNFSF101143239311998 10549288 11094155 Affinity Capture-MS; Co-crystal Structure; Reconstituted Complex
TNFRSF10BFADD1143029430227 11940602 15659383 Affinity Capture-Western; Co-purification
TNFRSF10BFADD1143239430227 11940602 15659383 Affinity Capture-Western; Co-purification
CFLARTNFRSF10B1143649325248 11940602 Affinity Capture-Western
CFLARTNFRSF10B1143239325248 11940602 Affinity Capture-Western
TIMM50TNFRSF10B12496115044455 Two-hybrid
TIMM50TNFRSF10B11432315044455 Two-hybrid
AlzGene, PDGene and SZGene Top
Animal Model Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018