AutismKB 2.0

Annotation Details for IL18R1


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Basic Information Top
Gene Symbol:IL18R1 ( CD218a,CDw218a,IL-1Rrp,IL18RA,IL1RRP )
Gene Full Name: interleukin 18 receptor 1
Band: 2q12.1
Quick LinksEntrez ID:8809; OMIM: 604494; Uniprot ID:IL18R_HUMAN; ENSEMBL ID: ENSG00000115604; HGNC ID: 5988
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005886TAS-plasma membrane-
GO:0016021IEA-integral component of membrane-
GO ID Evidence Qualifier GO_term References
GO:0004872TAS-receptor activity9325300
GO:0004908IEA-interleukin-1 receptor activity-
GO:0005515IPI-protein binding25261253
GO:0042008IEA-interleukin-18 receptor activity-
GO ID Evidence Qualifier GO_term References
GO:0006955TAS-immune response9325300
GO:0007165TAS-signal transduction9325300
GO:0030101IEA-natural killer cell activation-
GO:0032729IEA-positive regulation of interferon-gamma production-
GO:0035655IEA-interleukin-18-mediated signaling pathway-
GO:0042346IEA-positive regulation of NF-kappaB import into nucleus-
GO:0045063IEA-T-helper 1 cell differentiation-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
IL18R1IL1RAP1143378626725 Reconstituted Complex
IL18R1IL1RAP1097718626725 Reconstituted Complex
IL1F7IL18R111433712096920 Reconstituted Complex
IL1F7IL18R111805412096920 Reconstituted Complex
No data
No data
AlzGene, PDGene and SZGene Top
No data
No data
Gene Symbol Poly Names Gene overview in SZGene
IL18R1rs11465572, rs11465576, rs11465597, rs11465608, rs1420095, rs2241116, rs4851570, rs6543124, rs7558013, rs7579737, rs9308857 Gene overview in SZGene
Animal Model Top
  • MGI ID: MGI:105383
  • Data Attributes: MGI curated and HomoloGene calculated
No data
No data

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  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018