AutismKB 2.0

Annotation Details for AKAP4


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:AKAP4 ( AKAP 82,AKAP-4,AKAP82,CT99,FSC1,HI,PRKA4,hAKAP82,p82 )
Gene Full Name: A kinase (PRKA) anchor protein 4
Band: Xp11.22
Quick LinksEntrez ID:8852; OMIM: 300185; Uniprot ID:AKAP4_HUMAN; ENSEMBL ID: ENSG00000147081; HGNC ID: 374
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634IDA-nucleus21630459
GO:0005737IBA-cytoplasm-
GO:0005856TAS-cytoskeleton9822690
GO:0005952NAS-cAMP-dependent protein kinase complex9822690
GO:0030018IEA-Z disc-
GO:0031514IDA-motile cilium9822690
GO:0035686IBA-sperm fibrous sheath-
GO:0048471IEA-perinuclear region of cytoplasm-
GO:0097228IBA-sperm principal piece-
GO ID Evidence Qualifier GO_term References
GO:0051018IBA-protein kinase A binding-
GO:0051018ISS-protein kinase A binding-
GO ID Evidence Qualifier GO_term References
GO:0006928TAS-movement of cell or subcellular component9822690
GO:0007165TAS-signal transduction9822690
GO:0007178IEA-transmembrane receptor protein serine/threonine kinase signaling pathway-
GO:0007338TAS-single fertilization9822690
GO:0010738IBA-regulation of protein kinase A signaling-
GO:0030317IMP-flagellated sperm motility9822690
GO:0044458IEA-motile cilium assembly-
GO:0045184IEA-establishment of protein localization-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
AKAP4PRKAR1A1143779852104 12606363 Reconstituted Complex; Two-hybrid
AKAP4PRKAR1A1115599852104 12606363 Reconstituted Complex; Two-hybrid
AKAP4PRKAR2A1115629852104 Reconstituted Complex
AKAP4PRKAR2A1143779852104 Reconstituted Complex
AKAP3AKAP411581712606363 Reconstituted Complex; Two-hybrid
AKAP3AKAP411437712606363 Reconstituted Complex; Two-hybrid
FSIP1AKAP412780512606363 Two-hybrid
FSIP1AKAP411437712606363 Two-hybrid
FSIP2AKAP411437712606363 Two-hybrid
FSIP2AKAP413487312606363 Two-hybrid
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:102794
  • Data Attributes: MGI curated and HomoloGene calculated
No data
No data

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018