AutismKB 2.0

Annotation Details for LDB1


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Basic Information Top
Gene Symbol:LDB1 ( CLIM2,NLI )
Gene Full Name: LIM domain binding 1
Band: 10q24.32
Quick LinksEntrez ID:8861; OMIM: 603451; Uniprot ID:LDB1_HUMAN; ENSEMBL ID: ENSG00000198728; HGNC ID: 6532
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0000790IDA-nuclear chromatin20855495
GO:0005634ISS-nucleus-
GO:0005667IDA-transcription factor complex16314316
GO:0031252ISS-cell leading edge-
GO:0043234ISS-protein complex-
GO ID Evidence Qualifier GO_term References
GO:0001102IPI-RNA polymerase II activating transcription factor binding16314316
GO:0001158IEA-enhancer sequence-specific DNA binding-
GO:0003682IEA-chromatin binding-
GO:0003714TAS-transcription corepressor activity9391090
GO:0005515IPI-protein binding15231748
GO:0019899IPI-enzyme binding23382074
GO:0030274IPI-LIM domain binding12792813
GO:0030274ISS-LIM domain binding-
GO:0042803ISS-protein homodimerization activity-
GO:0043621IEA-protein self-association-
GO ID Evidence Qualifier GO_term References
GO:0000972ISS-transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery-
GO:0001702IEA-gastrulation with mouth forming second-
GO:0001942IEA-hair follicle development-
GO:0006351NAS-transcription, DNA-templated12792813
GO:0006355NAS-regulation of transcription, DNA-templated12792813
GO:0006366IEA-transcription from RNA polymerase II promoter-
GO:0007275NAS-multicellular organism development12792813
GO:0009948IEA-anterior/posterior axis specification-
GO:0010669IEA-epithelial structure maintenance-
GO:0016055IEA-Wnt signaling pathway-
GO:0021702IEA-cerebellar Purkinje cell differentiation-
GO:0022607IEA-cellular component assembly-
GO:0030182ISS-neuron differentiation-
GO:0030334ISS-regulation of cell migration-
GO:0032784ISS-regulation of DNA-templated transcription, elongation-
GO:0035019IEA-somatic stem cell population maintenance-
GO:0043549ISS-regulation of kinase activity-
GO:0043973ISS-histone H3-K4 acetylation-
GO:0045647ISS-negative regulation of erythrocyte differentiation-
GO:0045785IEA-positive regulation of cell adhesion-
GO:0045892IDA-negative regulation of transcription, DNA-templated10767331
GO:0045944IMP-positive regulation of transcription from RNA polymerase II promoter20855495
GO:0045944ISS-positive regulation of transcription from RNA polymerase II promoter-
GO:0046985ISS-positive regulation of hemoglobin biosynthetic process-
GO:0051893ISS-regulation of focal adhesion assembly-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
LDB1CBFA2T311438416407974 Affinity Capture-Western
LDB1CBFA2T310731116407974 Affinity Capture-Western
LDB1ESR110840319117995 Reconstituted Complex
LDB1ESR111438419117995 Reconstituted Complex
LDB1LMO211019112727888 17437998 Affinity Capture-Western
LDB1LMO211438412727888 17437998 Affinity Capture-Western
LDB1SP111255012239153 Reconstituted Complex
LDB1SP111438412239153 Reconstituted Complex
LDB1TAL111274916407974 Affinity Capture-MS; Affinity Capture-Western
LDB1TAL111438416407974 Affinity Capture-MS; Affinity Capture-Western
LDB1TCF311279116407974 Affinity Capture-Western
LDB1TCF311438416407974 Affinity Capture-Western
LDB1LMO411411312727888 12925972 Affinity Capture-Western; Co-crystal Structure
LDB1LMO411438412727888 12925972 Affinity Capture-Western; Co-crystal Structure
SSBP4LDB112800616189514 Two-hybrid
SSBP4LDB111438416189514 Two-hybrid
SSBP2LDB111716416189514 Two-hybrid
SSBP2LDB111438416189514 Two-hybrid
TOLLIPLDB111438416189514 Two-hybrid
TOLLIPLDB111997816189514 Two-hybrid
LMO3LDB111438416189514 Two-hybrid
LMO3LDB112097716189514 Two-hybrid
RLIMLDB111931917437998 Affinity Capture-Western
RLIMLDB111438417437998 Affinity Capture-Western
LHX2LDB111475820211142 Two-hybrid
LHX2LDB111438420211142 Two-hybrid
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:894762
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-990415-138'