AutismKB 2.0

Annotation Details for IER3


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Basic Information Top
Gene Symbol:IER3 ( DIF-2,DIF2,GLY96,IEX-1,IEX-1L,IEX1,PRG1 )
Gene Full Name: immediate early response 3
Band: 6p21.33
Quick LinksEntrez ID:8870; OMIM: 602996; Uniprot ID:IEX1_HUMAN; ENSEMBL ID: ENSG00000137331; HGNC ID: 5392
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634IDA-nucleus20467439
GO:0005829TAS-cytosol-
GO:0016021IEA-integral component of membrane-
GO ID Evidence Qualifier GO_term References
GO:0005515IPI-protein binding15451437
GO ID Evidence Qualifier GO_term References
GO:0006915TAS-apoptotic process9196025
GO:0009653TAS-anatomical structure morphogenesis9196025
GO:0010941IBA-regulation of cell death-
GO:0014066TAS-regulation of phosphatidylinositol 3-kinase signaling-
GO:0043066IEA-negative regulation of apoptotic process-
GO:2001020IMP-regulation of response to DNA damage stimulus20467439
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
IER3MAPK111439012356731 Biochemical Activity
IER3MAPK111158012356731 Biochemical Activity
IER3MAPK311439012356731 Affinity Capture-Western
IER3MAPK311158112356731 Affinity Capture-Western
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:104814
  • Data Attributes: HomoloGene calculated
No data
No data

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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018