AutismKB 2.0

Annotation Details for HERC2


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Basic Information Top
Gene Symbol:HERC2 ( D15F37S1,DKFZp547P028,KIAA0393,SHEP1,jdf2,p528 )
Gene Full Name: hect domain and RLD 2
Band: 15q13.1
Quick LinksEntrez ID:8924; OMIM: 605837; Uniprot ID:HERC2_HUMAN; ENSEMBL ID: ENSG00000128731; HGNC ID: 4868
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634IDA-nucleus20304803
GO:0005654TAS-nucleoplasm-
GO:0005737IDA-cytoplasm20304803
GO:0005743IEA-mitochondrial inner membrane-
GO:0005814IEA-centriole-
GO:0016020IDA-membrane19946888
GO ID Evidence Qualifier GO_term References
GO:0004842IDA-ubiquitin-protein transferase activity20304803
GO:0005085NAS-guanyl-nucleotide exchange factor activity9949213
GO:0005515IPI-protein binding20023648
GO:0008270IEA-zinc ion binding-
GO:0031625IPI-ubiquitin protein ligase binding22508508
GO:0032183IDA-SUMO binding22508508
GO ID Evidence Qualifier GO_term References
GO:0006303TAS-double-strand break repair via nonhomologous end joining-
GO:0006886NAS-intracellular protein transport9949213
GO:0006974IDA-cellular response to DNA damage stimulus22508508
GO:0007283IEA-spermatogenesis-
GO:0016567IDA-protein ubiquitination20304803
GO:0016567IEA-protein ubiquitination-
GO:0043547IEA-positive regulation of GTPase activity-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
HERC2CDC4211443820936779 Two-hybrid
HERC2CDC4210743320936779 Two-hybrid
HERC2PMS111443817148452 Affinity Capture-Western
HERC2PMS111139117148452 Affinity Capture-Western
DBNLHERC211880917353931 Affinity Capture-MS
DBNLHERC211443817353931 Affinity Capture-MS
MPDU1HERC211490217353931 Affinity Capture-MS
MPDU1HERC211443817353931 Affinity Capture-MS
USP16HERC211584819615732 Affinity Capture-MS
USP16HERC211443819615732 Affinity Capture-MS
USP20HERC211443819615732 Affinity Capture-MS
USP20HERC211607719615732 Affinity Capture-MS
USP19HERC211607819615732 Affinity Capture-MS
USP19HERC211443819615732 Affinity Capture-MS
ZRANB1HERC212013919615732 Affinity Capture-MS
ZRANB1HERC211443819615732 Affinity Capture-MS
USP42HERC211443819615732 Affinity Capture-MS
USP42HERC212390419615732 Affinity Capture-MS
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:103234
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-070718-6'