AutismKB 2.0

Annotation Details for HERC1


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Basic Information Top
Gene Symbol:HERC1 ( p532,p619 )
Gene Full Name: hect (homologous to the E6-AP (UBE3A) carboxyl terminus) domain and RCC1 (CHC1)-like domain (RLD) 1
Band: 15q22.31
Quick LinksEntrez ID:8925; OMIM: 605109; Uniprot ID:HERC1_HUMAN; ENSEMBL ID: ENSG00000103657; HGNC ID: 4867
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005737TAS-cytoplasm8861955
GO:0005794IEA-Golgi apparatus-
GO:0005829IEA-cytosol-
GO:0016020IEA-membrane-
GO ID Evidence Qualifier GO_term References
GO:0004842IEA-ubiquitin-protein transferase activity-
GO:0005086TAS-ARF guanyl-nucleotide exchange factor activity8861955
GO ID Evidence Qualifier GO_term References
GO:0006810IEA-transport-
GO:0010507IEA-negative regulation of autophagy-
GO:0016567IEA-protein ubiquitination-
GO:0021702IEA-cerebellar Purkinje cell differentiation-
GO:0031175IEA-neuron projection development-
GO:0043547IEA-positive regulation of GTPase activity-
GO:0050885IEA-neuromuscular process controlling balance-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
HERC1DFFA11443917353931 Affinity Capture-MS
HERC1DFFA10804017353931 Affinity Capture-MS
HERC1PKM211133212650930 Reconstituted Complex; Two-hybrid
HERC1PKM211443912650930 Reconstituted Complex; Two-hybrid
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:2384589
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-030131-8542'