AutismKB 2.0

Annotation Details for FGD3


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Basic Information Top
Gene Symbol:FGD3 ( FLJ00004,MGC117260,ZFYVE5 )
Gene Full Name: FYVE, RhoGEF and PH domain containing 3
Band: 9q22.31
Quick LinksEntrez ID:89846; OMIM: NA; Uniprot ID:FGD3_HUMAN; ENSEMBL ID: ENSG00000127084; HGNC ID: 16027
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0001726ISS-ruffle-
GO:0005737ISS-cytoplasm-
GO:0005794ISS-Golgi apparatus-
GO:0005829TAS-cytosol-
GO:0005856IEA-cytoskeleton-
GO:0030027ISS-lamellipodium-
GO ID Evidence Qualifier GO_term References
GO:0005085ISS-guanyl-nucleotide exchange factor activity-
GO:0005085TAS-guanyl-nucleotide exchange factor activity-
GO:0005089TAS-Rho guanyl-nucleotide exchange factor activity-
GO:0031267ISS-small GTPase binding-
GO:0046872IEA-metal ion binding-
GO ID Evidence Qualifier GO_term References
GO:0007010ISS-cytoskeleton organization-
GO:0008360ISS-regulation of cell shape-
GO:0030036ISS-actin cytoskeleton organization-
GO:0035023IEA-regulation of Rho protein signal transduction-
GO:0043065TAS-positive regulation of apoptotic process-
GO:0043087ISS-regulation of GTPase activity-
GO:0043547IEA-positive regulation of GTPase activity-
GO:0046847ISS-filopodium assembly-
GO:0051056TAS-regulation of small GTPase mediated signal transduction-
Protein-Protein Interaction Top
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1353657
  • Data Attributes: MGI curated and HomoloGene calculated
No data
No data

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  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018