AutismKB 2.0

Annotation Details for MPZL1


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Basic Information Top
Gene Symbol:MPZL1 ( FLJ21047,MPZL1b,PZR,PZR1b,PZRa,PZRb )
Gene Full Name: myelin protein zero-like 1
Band: 1q24.2
Quick LinksEntrez ID:9019; OMIM: 604376; Uniprot ID:MPZL1_HUMAN; ENSEMBL ID: ENSG00000197965; HGNC ID: 7226
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005887IEA-integral component of plasma membrane-
GO:0005925IDA-focal adhesion21423176
GO:0009986IDA-cell surface19581412
GO ID Evidence Qualifier GO_term References
GO:0005198TAS-structural molecule activity9792637
GO:0005515IPI-protein binding9792637
GO ID Evidence Qualifier GO_term References
GO:0007169TAS-transmembrane receptor protein tyrosine kinase signaling pathway10681522
GO:0007267TAS-cell-cell signaling9792637
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
MPZL1PTPN111117459792637 Affinity Capture-Western
MPZL1PTPN111144869792637 Affinity Capture-Western
MPZL1SRC11259211751924 Affinity Capture-Western
MPZL1SRC11448611751924 Affinity Capture-Western
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AlzGene, PDGene and SZGene Top
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Gene Symbol Poly Names Gene overview in SZGene
MPZL1rs10918754, rs1933072, rs2051656, rs2213883, rs3752606, rs3767444, rs3767445, rs4145462, rs4472738, rs4657704, rs4657713 Gene overview in SZGene
Animal Model Top
  • MGI ID: MGI:1915731
  • Data Attributes: HomoloGene calculated
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018