AutismKB 2.0

Annotation Details for PKD2L1


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Basic Information Top
Gene Symbol:PKD2L1 ( PCL,PKD2L,PKDL,TRPP3 )
Gene Full Name: polycystic kidney disease 2-like 1
Band: 10q24.31
Quick LinksEntrez ID:9033; OMIM: 604532; Uniprot ID:PK2L1_HUMAN; ENSEMBL ID: ENSG00000107593; HGNC ID: 9011
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005783ISS-endoplasmic reticulum-
GO:0005886IDA-plasma membrane20538909
GO:0005886IMP-plasma membrane17944866
GO:0009986ISScolocalizes_withcell surface-
GO:0016020IDA-membrane19812697
GO:0016021NAS-integral component of membrane9748274
GO:0034704IDA-calcium channel complex24336289
GO:0043231IDA-intracellular membrane-bounded organelle17944866
GO:0043235ISS-receptor complex-
GO:0060170IEA-ciliary membrane-
GO:0097730IDA-non-motile cilium24336289
GO ID Evidence Qualifier GO_term References
GO:0005227IDA-calcium activated cation channel activity10517637
GO:0005261IDA-cation channel activity17944866
GO:0005262IDA-calcium channel activity24336289
GO:0005272IDA-sodium channel activity10517637
GO:0005509IDA-calcium ion binding22193359
GO:0005509ISS-calcium ion binding-
GO:0005515IPI-protein binding12525172
GO:0008092IPI-cytoskeletal protein binding12809519
GO:0008324ISScontributes_tocation transmembrane transporter activity-
GO:0015269IDA-calcium-activated potassium channel activity10517637
GO:0033040ISScontributes_tosour taste receptor activity-
GO:0042802ISS-identical protein binding-
GO:0051371IPI-muscle alpha-actinin binding17944866
GO:0051393IPI-alpha-actinin binding17944866
GO ID Evidence Qualifier GO_term References
GO:0001581ISS-detection of chemical stimulus involved in sensory perception of sour taste-
GO:0006812ISS-cation transport-
GO:0007224ISS-smoothened signaling pathway-
GO:0035725IDA-sodium ion transmembrane transport10517637
GO:0050915IMP-sensory perception of sour taste19812697
GO:0050982IBA-detection of mechanical stimulus-
GO:0070207IDA-protein homotrimerization22193359
GO:0070588IEA-calcium ion transmembrane transport-
GO:0071468ISS-cellular response to acidic pH-
GO:0071805IDA-potassium ion transmembrane transport10517637
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
PKD2L1TNNI111449912809519 Reconstituted Complex
PKD2L1TNNI111298912809519 Reconstituted Complex
PKD2L1TNNI311449912809519 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
PKD2L1TNNI311299112809519 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1352448
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-030616-558'