AutismKB 2.0

Annotation Details for SEMA5A


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Basic Information Top
Gene Symbol:SEMA5A ( FLJ12815,SEMAF,semF )
Gene Full Name: sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
Band: 5p15.31
Quick LinksEntrez ID:9037; OMIM: 609297; Uniprot ID:SEM5A_HUMAN; ENSEMBL ID: ENSG00000112902; HGNC ID: 10736
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005886TAS-plasma membrane-
GO:0016020ISS-membrane-
GO:0016021IEA-integral component of membrane-
GO:0070062IDA-extracellular exosome23376485
GO ID Evidence Qualifier GO_term References
GO:0030215ISS-semaphorin receptor binding-
GO:0035373ISS-chondroitin sulfate proteoglycan binding-
GO:0043395ISS-heparan sulfate proteoglycan binding-
GO:0045545ISS-syndecan binding-
GO ID Evidence Qualifier GO_term References
GO:0001938ISS-positive regulation of endothelial cell proliferation-
GO:0002043ISS-blood vessel endothelial cell proliferation involved in sprouting angiogenesis-
GO:0007155TAS-cell adhesion9049630
GO:0007162ISS-negative regulation of cell adhesion-
GO:0007267TAS-cell-cell signaling9464278
GO:0007399TAS-nervous system development9464278
GO:0007413ISS-axonal fasciculation-
GO:0021536ISS-diencephalon development-
GO:0030836ISS-positive regulation of actin filament depolymerization-
GO:0035413ISS-positive regulation of catenin import into nucleus-
GO:0045766ISS-positive regulation of angiogenesis-
GO:0048842ISS-positive regulation of axon extension involved in axon guidance-
GO:0048843ISS-negative regulation of axon extension involved in axon guidance-
GO:0050918ISS-positive chemotaxis-
GO:0051897ISS-positive regulation of protein kinase B signaling-
GO:0060326ISS-cell chemotaxis-
GO:1990256ISS-signal clustering-
GO:2000352ISS-negative regulation of endothelial cell apoptotic process-
GO:2001028ISS-positive regulation of endothelial cell chemotaxis-
Protein-Protein Interaction Top
AlzGene, PDGene and SZGene Top
No data
Gene Symbol Poly Names Gene overview in PDGene
SEMA5Ars12658266, rs1806151, rs368226, rs3798097, rs7702187, rs786843 Gene overview in PDGene
No data
Animal Model Top
  • MGI ID: MGI:107556
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-030131-8969'