AutismKB 2.0

Annotation Details for CLDN1


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Basic Information Top
Gene Symbol:CLDN1 ( CLD1,ILVASC,SEMP1 )
Gene Full Name: claudin 1
Band: 3q28
Quick LinksEntrez ID:9076; OMIM: 603718; Uniprot ID:CLD1_HUMAN; ENSEMBL ID: ENSG00000163347; HGNC ID: 2032
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005737IEA-cytoplasm-
GO:0005887IMP-integral component of plasma membrane23407391
GO:0005923IDA-bicellular tight junction20375010
GO:0005923ISS-bicellular tight junction-
GO:0016021TAS-integral component of membrane9931503
GO:0016323IDA-basolateral plasma membrane20375010
GO:0016324IEA-apical plasma membrane-
GO:0016328IEA-lateral plasma membrane-
GO ID Evidence Qualifier GO_term References
GO:0001618IMP-virus receptor activity20375010
GO:0005198IEA-structural molecule activity-
GO:0005515IPI-protein binding20375010
GO:0042802ISS-identical protein binding-
GO ID Evidence Qualifier GO_term References
GO:0007568IEA-aging-
GO:0008065IEA-establishment of blood-nerve barrier-
GO:0009636IEA-response to toxic substance-
GO:0016338ISS-calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules-
GO:0032496IEA-response to lipopolysaccharide-
GO:0042538IEA-hyperosmotic salinity response-
GO:0045216IMP-cell-cell junction organization20164257
GO:0045471IEA-response to ethanol-
GO:0046718IEA-viral entry into host cell-
GO:0051260IMP-protein homooligomerization25849148
GO:0051291IGI-protein heterooligomerization25849148
GO:0061436IMP-establishment of skin barrier23407391
GO:0061772IEA-drug transport across blood-nerve barrier-
GO:0070673IEA-response to interleukin-18-
GO:0070830IMP-bicellular tight junction assembly25849148
GO:0071284IEA-cellular response to lead ion-
GO:0071346IEA-cellular response to interferon-gamma-
GO:0071356IEA-cellular response to tumor necrosis factor-
GO:0071548IEA-response to dexamethasone-
GO:0071560IEA-cellular response to transforming growth factor beta stimulus-
GO:0090557IEA-establishment of endothelial intestinal barrier-
GO:0097421IEA-liver regeneration-
GO:1903348IEA-positive regulation of bicellular tight junction assembly-
GO:1903545IEA-cellular response to butyrate-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
CLDN1CLDN311453312909588 Affinity Capture-Western
CLDN1CLDN310775712909588 Affinity Capture-Western
CLDN1TJP111453310601346 Reconstituted Complex
CLDN1TJP111293710601346 Reconstituted Complex
CLDN1CLDN511453312909588 Affinity Capture-Western
CLDN1CLDN511297712909588 Affinity Capture-Western
TJP3CLDN111802510601346 Reconstituted Complex
TJP3CLDN111453310601346 Reconstituted Complex
TJP2CLDN111480910601346 Reconstituted Complex
TJP2CLDN111453310601346 Reconstituted Complex
INADLCLDN111453312021270 Reconstituted Complex
INADLCLDN111550212021270 Reconstituted Complex
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1276109
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-010328-11'