Gene Symbol:	USP2 ( UBP41,USP9 )
Gene Full Name:	ubiquitin specific peptidase 2
Band:	11q23.3
Quick Links	Entrez ID:9099; OMIM: 604725; Uniprot ID:UBP2_HUMAN; ENSEMBL ID: ENSG00000036672; HGNC ID: 12618
Relate to Another Database:	SFARIGene; denovo-db

GO ID	Evidence	Qualifier	GO_term	References
GO:0005654	TAS	-	nucleoplasm	-
GO:0005813	IEA	-	centrosome	-
GO:0005938	IEA	-	cell cortex	-
GO:0048471	IEA	-	perinuclear region of cytoplasm	-

GO ID	Evidence	Qualifier	GO_term	References
GO:0004197	TAS	-	cysteine-type endopeptidase activity	9827704
GO:0004843	IDA	-	thiol-dependent ubiquitin-specific protease activity	17290220
GO:0005515	IPI	-	protein binding	16189514
GO:0030332	IPI	-	cyclin binding	19917254
GO:0031625	IPI	-	ubiquitin protein ligase binding	17290220
GO:0036459	TAS	-	thiol-dependent ubiquitinyl hydrolase activity	-
GO:0042802	IEA	-	identical protein binding	-
GO:0046872	IEA	-	metal ion binding	-

GO ID	Evidence	Qualifier	GO_term	References
GO:0000122	IMP	-	negative regulation of transcription from RNA polymerase II promoter	17290220
GO:0006511	IEA	-	ubiquitin-dependent protein catabolic process	-
GO:0007049	IEA	-	cell cycle	-
GO:0007517	IEA	-	muscle organ development	-
GO:0016579	IDA	-	protein deubiquitination	17290220
GO:0016579	TAS	-	protein deubiquitination	-
GO:0032922	ISS	-	circadian regulation of gene expression	-
GO:0043153	ISS	-	entrainment of circadian clock by photoperiod	-
GO:0045475	ISS	-	locomotor rhythm	-
GO:0045931	IMP	-	positive regulation of mitotic cell cycle	17290220
GO:0048512	ISS	-	circadian behavior	-
GO:0050821	IDA	-	protein stabilization	17290220
GO:0050821	IMP	-	protein stabilization	19838211

Gene Symbol	Interactant	Interaction ID	References	Description
USP2	FASN	114553	15050917	Affinity Capture-MS; Biochemical Activity; Reconstituted Complex
USP2	FASN	108488	15050917	Affinity Capture-MS; Biochemical Activity; Reconstituted Complex
USP2	KRT15	110064	16189514	Affinity Capture-Western; Two-hybrid
USP2	KRT15	114553	16189514	Affinity Capture-Western; Two-hybrid
USP2	NFKB2	114553	14743216	Affinity Capture-MS
USP2	NFKB2	110858	14743216	Affinity Capture-MS
USP2	TRAF2	114553	16189514	Two-hybrid
USP2	TRAF2	113038	16189514	Two-hybrid
USP2	UBC	113164	16905103	Co-crystal Structure
USP2	UBC	114553	16905103	Co-crystal Structure
CCDC85B	USP2	114553	16189514	Two-hybrid
CCDC85B	USP2	116198	16189514	Two-hybrid
HOOK2	USP2	118957	16189514	Two-hybrid
HOOK2	USP2	114553	16189514	Two-hybrid
BEGAIN	USP2	121647	16189514	Two-hybrid
BEGAIN	USP2	114553	16189514	Two-hybrid
BEND5	USP2	122782	16189514	Two-hybrid
BEND5	USP2	114553	16189514	Two-hybrid
RRP15	USP2	114553	19615732	Affinity Capture-MS
RRP15	USP2	119224	19615732	Affinity Capture-MS
LONP1	USP2	114762	19615732	Affinity Capture-MS
LONP1	USP2	114553	19615732	Affinity Capture-MS

AutismKB 2.0

Annotation Details for USP2