AutismKB 2.0

Annotation Details for CREB3L1


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Basic Information Top
Gene Symbol:CREB3L1 ( OASIS )
Gene Full Name: cAMP responsive element binding protein 3-like 1
Band: 11p11.2
Quick LinksEntrez ID:90993; OMIM: NA; Uniprot ID:CR3L1_HUMAN; ENSEMBL ID: ENSG00000157613; HGNC ID: 18856
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634IDA-nucleus25310401
GO:0005634ISS-nucleus-
GO:0005783IDA-endoplasmic reticulum16236796
GO:0005789IEA-endoplasmic reticulum membrane-
GO:0016020IDA-membrane25310401
GO:0016021IEA-integral component of membrane-
GO ID Evidence Qualifier GO_term References
GO:0001077ISS-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-
GO:0003682ISS-chromatin binding-
GO:0005515IPI-protein binding21516116
GO:0035497ISS-cAMP response element binding-
GO:0044212ISS-transcription regulatory region DNA binding-
GO:0046332IPI-SMAD binding25310401
GO ID Evidence Qualifier GO_term References
GO:0001649ISS-osteoblast differentiation-
GO:0006366IEA-transcription from RNA polymerase II promoter-
GO:0007275IEA-multicellular organism development-
GO:0030968ISS-endoplasmic reticulum unfolded protein response-
GO:0032967IDA-positive regulation of collagen biosynthetic process25310401
GO:0070278ISS-extracellular matrix constituent secretion-
GO:1902236ISS-negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway-
GO:1990440ISS-positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress-
Protein-Protein Interaction Top
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1347062
  • Data Attributes: MGI curated and HomoloGene calculated
No data
No data

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  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018