AutismKB 2.0

Annotation Details for SMC3


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Basic Information Top
Gene Symbol:SMC3 ( BAM,BMH,CDLS3,CSPG6,HCAP,SMC3L1 )
Gene Full Name: structural maintenance of chromosomes 3
Band: 10q25.2
Quick LinksEntrez ID:9126; OMIM: 606062; Uniprot ID:SMC3_HUMAN; ENSEMBL ID: ENSG00000108055; HGNC ID: 2468
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0000775TAS-chromosome, centromeric region-
GO:0000785IDA-chromatin16682347
GO:0000800IEA-lateral element-
GO:0000922IDA-spindle pole11590136
GO:0005604TAS-basement membrane8621634
GO:0005622IDA-intracellular12651860
GO:0005634TAS-nucleus9506951
GO:0005654IDA-nucleoplasm-
GO:0005654TAS-nucleoplasm-
GO:0005694TAS-chromosome-
GO:0005737IDA-cytoplasm11590136
GO:0005829TAS-cytosol-
GO:0008278NAS-cohesin complex9506951
GO:0016363IDA-nuclear matrix11590136
GO:0030893IDA-meiotic cohesin complex21242291
GO:0034991IEA-nuclear meiotic cohesin complex-
GO ID Evidence Qualifier GO_term References
GO:0003682IEA-chromatin binding-
GO:0003777NAS-microtubule motor activity11590136
GO:0005515IPI-protein binding9506951
GO:0005524IEA-ATP binding-
GO:0036033IEA-mediator complex binding-
GO:0046982IPI-protein heterodimerization activity11590136
GO:0070840IDA-dynein complex binding11590136
GO ID Evidence Qualifier GO_term References
GO:0000278TAS-mitotic cell cycle9506951
GO:0006275IMP-regulation of DNA replication19907496
GO:0006281IEA-DNA repair-
GO:0007062IMP-sister chromatid cohesion15917200
GO:0007062NAS-sister chromatid cohesion11590136
GO:0007062TAS-sister chromatid cohesion-
GO:0007064IEA-mitotic sister chromatid cohesion-
GO:0019827IEA-stem cell population maintenance-
GO:0032876IMP-negative regulation of DNA endoreduplication15917200
GO:0044791IDA-positive regulation by host of viral release from host cell19444697
GO:0051301IEA-cell division-
GO:0051321IDA-meiotic cell cycle12498344
GO:0051702IDA-interaction with symbiont19444697
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
SMC3APC11457420936779 Two-hybrid
SMC3APC10682120936779 Two-hybrid
SMC3AIRE10682320085707 Affinity Capture-MS
SMC3AIRE11457420085707 Affinity Capture-MS
SMC3ATM11457417478428 Affinity Capture-Western
SMC3ATM10696217478428 Affinity Capture-Western
SMC3CASP411457417353931 Affinity Capture-MS
SMC3CASP410728717353931 Affinity Capture-MS
SMC3CDK411457417353931 Affinity Capture-MS
SMC3CDK410745417353931 Affinity Capture-MS
SMC3HDAC211457412198550 Co-purification
SMC3HDAC210931612198550 Co-purification
SMC3MXD11145749528857 Reconstituted Complex; Two-hybrid
SMC3MXD11102599528857 Reconstituted Complex; Two-hybrid
SMC3MXI11145749528857 Reconstituted Complex; Two-hybrid
SMC3MXI11106869528857 Reconstituted Complex; Two-hybrid
SMC3NUMA111457411590136 Affinity Capture-Western
SMC3NUMA111098011590136 Affinity Capture-Western
SMC3PMS111457417148452 Affinity Capture-Western
SMC3PMS111139117148452 Affinity Capture-Western
SMC3RPGR11457416043481 Affinity Capture-Western; Reconstituted Complex
SMC3RPGR11203016043481 Affinity Capture-Western; Reconstituted Complex
SMC3SMC1A1145749789013 11590136 11877376 12759374 Affinity Capture-Western
SMC3SMC1A1138719789013 11590136 11877376 12759374 Affinity Capture-Western
SMC3SMARCA511457412198550 Co-purification
SMC3SMARCA511404512198550 Co-purification
SMC3RAE111457418832153 Affinity Capture-Western
SMC3RAE111405418832153 Affinity Capture-Western
SMC3BECN111457420562859 Affinity Capture-MS
SMC3BECN111422620562859 Affinity Capture-MS
SMC3USP1311446519615732 Affinity Capture-MS
SMC3USP1311457419615732 Affinity Capture-MS
KIFAP3SMC31165829506951 Reconstituted Complex; Two-hybrid
KIFAP3SMC31145749506951 Reconstituted Complex; Two-hybrid
MXD4SMC31158549528857 Reconstituted Complex; Two-hybrid
MXD4SMC31145749528857 Reconstituted Complex; Two-hybrid
MXD3SMC31145749528857 Reconstituted Complex; Two-hybrid
MXD3SMC31236589528857 Reconstituted Complex; Two-hybrid
STAG1SMC311556411076961 Co-purification
STAG1SMC311457411076961 Co-purification
STAG3SMC311595711483963 Affinity Capture-Western
STAG3SMC311457411483963 Affinity Capture-Western
TUBBSMC312844411590136 Affinity Capture-Western
TUBBSMC311457411590136 Affinity Capture-Western
SYCP3SMC311908112759374 Affinity Capture-Western
SYCP3SMC311457412759374 Affinity Capture-Western
REC8SMC311530612759374 Affinity Capture-Western
REC8SMC311457412759374 Affinity Capture-Western
CDCA5SMC312522515837422 Affinity Capture-Western; Reconstituted Complex
CDCA5SMC311457415837422 Affinity Capture-Western; Reconstituted Complex
SRRM1SMC311554416159877 Affinity Capture-MS; Co-fractionation
SRRM1SMC311457416159877 Affinity Capture-MS; Co-fractionation
FEZ1SMC311499716484223 Reconstituted Complex; Two-hybrid
FEZ1SMC311457416484223 Reconstituted Complex; Two-hybrid
FEZ2SMC311499616484223 Two-hybrid
FEZ2SMC311457416484223 Two-hybrid
NEK6SMC311457417353931 Affinity Capture-MS
NEK6SMC311600017353931 Affinity Capture-MS
MAGED1SMC311487917353931 Affinity Capture-MS
MAGED1SMC311457417353931 Affinity Capture-MS
PAXIP1SMC311457417925232 Affinity Capture-MS
PAXIP1SMC311662517925232 Affinity Capture-MS
WFDC5SMC312723619906707 Affinity Capture-Western
WFDC5SMC311457419906707 Affinity Capture-Western
PDS5ASMC311684819906707 Affinity Capture-Western
PDS5ASMC311457419906707 Affinity Capture-Western
CAMKK2SMC311588920562859 Affinity Capture-MS
CAMKK2SMC311457420562859 Affinity Capture-MS
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1339795
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-030131-3196'