AutismKB 2.0

Annotation Details for SLC6A5


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:SLC6A5 ( GLYT-2,GLYT2,NET1 )
Gene Full Name: solute carrier family 6 (neurotransmitter transporter, glycine), member 5
Band: 11p15.1
Quick LinksEntrez ID:9152; OMIM: 604159; Uniprot ID:SC6A5_HUMAN; ENSEMBL ID: ENSG00000165970; HGNC ID: 11051
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005886IDA-plasma membrane16751771
GO:0005886TAS-plasma membrane-
GO:0005887IBA-integral component of plasma membrane-
GO:0016021TAS-integral component of membrane9845349
GO ID Evidence Qualifier GO_term References
GO:0005328IEA-neurotransmitter:sodium symporter activity-
GO:0015375IDA-glycine:sodium symporter activity16751771
GO:0015375TAS-glycine:sodium symporter activity-
GO:0046872IEA-metal ion binding-
GO ID Evidence Qualifier GO_term References
GO:0006810TAS-transport9845349
GO:0006836IEA-neurotransmitter transport-
GO:0007268TAS-chemical synaptic transmission9845349
GO:0036233IDA-glycine import16751771
GO:0055085IEA-transmembrane transport-
GO:0060012IMP-synaptic transmission, glycinergic16751771
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
SLC6A5STX1A11459910722844 Affinity Capture-Western
SLC6A5STX1A11267610722844 Affinity Capture-Western
No data
No data
AlzGene, PDGene and SZGene Top
No data
No data
Gene Symbol Poly Names Gene overview in SZGene
SLC6A520597_(AC)n, rs1792970, rs2000959, rs2241940, rs3740871, rs3758807, rs3781742, rs3819252, rs894747 Gene overview in SZGene
Animal Model Top
  • MGI ID: MGI:105090
  • Data Attributes: MGI curated and HomoloGene calculated
No data
No data

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018