AutismKB 2.0

Annotation Details for IL1RL1


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Basic Information Top
Gene Symbol:IL1RL1 ( DER4,FIT-1,IL33R,MGC32623,ST2,ST2L,ST2V,T1 )
Gene Full Name: interleukin 1 receptor-like 1
Band: 2q12.1
Quick LinksEntrez ID:9173; OMIM: 601203; Uniprot ID:ILRL1_HUMAN; ENSEMBL ID: ENSG00000115602; HGNC ID: 5998
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005578IEA-proteinaceous extracellular matrix-
GO:0005886TAS-plasma membrane-
GO:0009897IEA-external side of plasma membrane-
GO:0016021IEA-integral component of membrane-
GO ID Evidence Qualifier GO_term References
GO:0002113IEA-interleukin-33 binding-
GO:0002114IEA-interleukin-33 receptor activity-
GO:0004896TAS-cytokine receptor activity10191101
GO:0004908IEA-interleukin-1 receptor activity-
GO:0005057TAS-signal transducer activity, downstream of receptor1482686
GO:0005515IPI-protein binding8621446
GO ID Evidence Qualifier GO_term References
GO:0002826IEA-negative regulation of T-helper 1 type immune response-
GO:0006955NAS-immune response10527832
GO:0007165TAS-signal transduction1482686
GO:0032689IEA-negative regulation of interferon-gamma production-
GO:0032754IEA-positive regulation of interleukin-5 production-
GO:0038172IEA-interleukin-33-mediated signaling pathway-
GO:0043032IEA-positive regulation of macrophage activation-
GO:0043124IEA-negative regulation of I-kappaB kinase/NF-kappaB signaling-
GO:0050729IEA-positive regulation of inflammatory response-
GO:0090197IEA-positive regulation of chemokine secretion-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
TMED1IL1RL11146138621446 Reconstituted Complex
TMED1IL1RL11162088621446 Reconstituted Complex
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:98427
  • Data Attributes: MGI curated and HomoloGene calculated
No data
No data

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  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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