AutismKB 2.0

Annotation Details for MAP3K13


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Basic Information Top
Gene Symbol:MAP3K13 ( LZK,MEKK13,MGC133196 )
Gene Full Name: mitogen-activated protein kinase kinase kinase 13
Band: 3q27.2
Quick LinksEntrez ID:9175; OMIM: 604915; Uniprot ID:M3K13_HUMAN; ENSEMBL ID: ENSG00000073803; HGNC ID: 6852
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0008385IDAcolocalizes_withIkappaB kinase complex12492477
GO:0016020IDA-membrane9353328
GO ID Evidence Qualifier GO_term References
GO:0004674IDA-protein serine/threonine kinase activity9353328
GO:0004709IDA-MAP kinase kinase kinase activity11726277
GO:0005515IPI-protein binding11726277
GO:0005524IEA-ATP binding-
GO:0019901ISS-protein kinase binding9353328
GO:0042802IPI-identical protein binding11163770
GO:0042803IDA-protein homodimerization activity11163770
GO:0046872IEA-metal ion binding-
GO ID Evidence Qualifier GO_term References
GO:0000186IDA-activation of MAPKK activity11726277
GO:0006468IDA-protein phosphorylation9353328
GO:0007254IDA-JNK cascade9353328
GO:0046777IDA-protein autophosphorylation9353328
GO:0051092IDA-positive regulation of NF-kappaB transcription factor activity12492477
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
MAP3K13IKBKB10976712492477 Affinity Capture-Western
MAP3K13IKBKB11461412492477 Affinity Capture-Western
MAP3K13MAP2K711461411726277 Biochemical Activity
MAP3K13MAP2K711159511726277 Biochemical Activity
MAP3K13MAP3K1311461411163770 Affinity Capture-Western
MAPK8IP1MAP3K1311461411726277 Affinity Capture-Western
MAPK8IP1MAP3K1311486411726277 Affinity Capture-Western
PRDX3MAP3K1311461412492477 Affinity Capture-Western; Two-hybrid
PRDX3MAP3K1311613612492477 Affinity Capture-Western; Two-hybrid
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:2444243
  • Data Attributes: HomoloGene calculated
No data